Targeting key regulators of innate immunity in inflammation-associated cancer

免疫系统的不受控制的调节促进了炎症相关的胰腺癌、胃癌和肺癌，这些癌症是世界上最常见的癌症之一。这些癌症的高死亡率很大程度上是由于在晚期发现较晚，沿着目前治疗的无效。我的项目旨在确定免疫系统的关键调节因子作为新的分子生物标志物（例如早期检测）和这些疾病的个性化治疗目标。

Uncontrolled regulation of the immune system promotes inflammation-associated pancreatic, stomach and lung cancers, which are among the most common cancers worldwide. The high death rate of these cancers is largely due to late detection at advanced stages, along with the ineffectiveness of current therapies. My project aims to identify key regulators of the immune system as novel molecular biomarkers (e.g. for early detection) and targets for personalised treatments in these diseases.