Targeting leukaemia stem cells through inhibition of telomerase

急性髓系白血病(AML)是一种侵袭性很强的血癌，每年导致多达1000名澳大利亚人死亡。我们使用化疗治疗AML，然而，大多数患者不是单靠化疗就能治愈的，疾病最终会复发(复发)。我们正在寻找一种针对白血病细胞内遗传物质(DNA)的AML患者的新型治疗方法。我们的工作表明，这种新型治疗方法可以防止化疗后复发。

Acute myeloid leukaemia (AML) is a type of very aggressive blood cancer that kills up to 1000 Australians every year. We use chemotherapy to treat AML, however, most patients are not cured by chemotherapy alone and the disease eventually comes back (relapses). We are looking at a new type of treatment for patients with AML that targets the genetic material (DNA) within the leukaemia cells. Our work has shown that this new type of treatment may prevent relapse after chemotherapy.