Understanding RAB39B-mediated Parkinson's disease

帕金森氏症(PD)是一种复杂的神经疾病，影响着10万澳大利亚人。帕金森病的主要临床特征是特定类型神经元的选择性丢失。目前尚不清楚为什么这些神经元优先丢失。我们发现了一种导致早发性帕金森病的新基因。这项研究将确定该基因的特征，并确定潜在的疾病机制。这些研究将使治疗帕金森病的新疗法的开发成为可能。

Parkinson’s disease (PD) is a complex neurological condition affecting 100,000 Australians. The primary clinical features of PD result from the selective loss of a specific type of neuron. It is currently unclear why these neurons are preferentially lost. We have identified a novel gene that causes early onset PD. This study will characterise the gene and determine the underlying disease mechanism. These studies will enable the development of novel therapies for treating PD.