Effects of a low humidity environment and visual tasking on tear film protein composition

眼泪是一种容易获得的体液，可以很容易地收集起来，而不会给患者造成任何不适。收集的泪水可以在实验室进行分析，从分析中获得的结果有可能告诉我们很多关于我们健康的信息。泪液测试，如各种蛋白质的水平，被用来确定人们是否有眼睛问题，如干眼。Inflamax Research Inc.是一家加拿大公司，该公司在安大略省密西索加市环球大道3121号开发了环境曝光室(EEC)，这是世界上为数不多的几个为眼科研究设计的实验室之一，也是加拿大唯一的一个。EEC是一种创新的设备，旨在控制温度、相对湿度和空气流动，以便为干眼研究建立标准化和可重复的环境。泪水将在接触前从患者身上收集，并在环境舱中暴露，泪水将在隐形眼镜研究中心生物科学实验室使用新技术进行分析，并将研究这些条件下的差异。该项目的结果将提供关于受控湿度、温度、气流、照明和视觉任务在改变泪膜蛋白质组成方面的作用的有价值的数据，该研究的结果将对加拿大具有重要的生物技术和生物医学应用。

Tears are a readily available body fluid that can be easily collected without causing any discomfort to the patient. The collected tears can be analyzed in the laboratory and the results obtained from this analysis have the potential to tell us a great deal about our health. Tear tests, such as the level of various proteins, are used to determine whether people have ocular problems such as dry eye. Inflamax Research Inc is a Canadian company which has developed an Environmental Exposure Chamber (EEC) at 3121 Universal Drive, Mississauga, Ontario, which is one of only a handful designed for ocular research in the world and the only one in Canada. The EEC is an innovative facility designed to control temperature, RH and air flow in order to establish standardized and reproducible environments for the study of dry eye. Tears will be collected from patients before and exposure in the environmental chamber and tears will be analyzed using novel techniques in the Centre for Contact Lens Research Biological Sciences laboratory and the differences in these conditions will be studied. The results from this project will provide valuable data on the role of controlled humidity, temperature, airflow, lighting and visual tasking in altering the tear film protein composition and the results from this study will have important biotechnology and biomedical applications for Canada.