Solute transport in fishes:- function and evolution

目前的发现提案调查了基础脊椎动物中离子、酸碱和溶质转运蛋白的功能进化。我们建议调查：1）负责允许淡水虹鳟鱼和斑马鱼侵入离子浓度低的沃茨的转运蛋白; 2）允许和限制鲨鱼进入半咸水沃茨的能力的转运蛋白; 3）太平洋盲鳗在机会性清除中的独特适应，包括对腐败环境的适应和溶质获取的相关独特方面; 4）溶质运输进化的基本性质，包括将这些特征整合到脊椎动物进化的当前进化理论中。这项研究将引起进化科学家、比较生理学家、渔业管理者和生物医学科学家的浓厚兴趣。

The present Discovery proposal investigates the functional evolution of ion, acid-base and solute transporters in basal vertebrates. We propose to investigate: 1) the transporters responsible for allowing freshwater rainbow trout and zebrafish to invade waters with low ion concentrations; 2) the transporters that both allow and limit sharks ability to enter brackish waters; 3) the unique adaptations in opportunistic scavenging Pacific hagfish, including adaptations to putrefying environments and associated unique aspects of solute acquisition and 4) the fundamental nature of the evolution of solute transport, including integration of these traits into current evolutionary theory of vertebrate evolution. The research will be of intense interest to evolutionary scientists, comparative physiologists, fisheries managers and biomedical scientists.