Liquid Scintillation counter for radiotracer studies

用于放射性示踪剂研究的液体闪烁计数器

• 批准号: RTI-2018-00526
• 负责人: Goss, Gregory
• 金额: $ 3.75万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642186
• 关键词: Liquid; Scintillation; counter; radiotracer; studies

This RTI application is for an automatic ß-counter that is crucially important for three highly successful and NSERC Discovery funded research programs of Professors Dr. Greg Goss, Dr. Chris Glover, and Dr. George Owttrim. Scintillation counting of radioactive ß -particles is one of the most sensitive methods of detection and the use of radioactive tracers is a fundamental component of each of the three-above-mentioned programs in animal or plant physiology. The researchers currently use an old Beckman LS-6500 ß-counter, first purchased in 1993, and this instrument has recently broken down. Similar failures in 2012 and 2010, the associated service costs, and the lack of availability of parts highlight the need for a new instrument, especially given it is essential to each of these programs. We require the requested equipment in our labs because we use techniques whose sensitivity requirements cannot be replaced by non-radioactive methods. Without a functional and reliable ß-counter, the continuance of NSERC (and other agency) funded research programs for Drs. Goss, Glover and Owttrim will be fatally hampered, including the research programs for a large number of HQP students and PDFs associated with these programs. The Hitachi AccuFLEX LSC-8000 liquid scintillation ß- counter (see Justification of equipment selected) provides significant advantages over the Perkin-Elmer machine with respect to sample handling and provision of a substantial and continuous reduction of liquid radioactive fluor and plastic production, in addition to the cost differential. In summary, the AccuFLEX LSC-8000 will meet the current requirements of the co-applicants and also potential use by future hires for the foreseeable future.

这个RTI应用程序是一个自动ß-计数器，它对三个非常成功的NSERC发现资助的研究项目至关重要，这些研究项目是由Greg Goss博士、Chris Glover博士和George Owttrim博士资助的。放射性β粒子的闪烁计数是最灵敏的检测方法之一，放射性示踪剂的使用是上述三种动物或植物生理学计划的基本组成部分。研究人员目前使用的是一台1993年首次购买的老贝克曼LS-6500计数器，这台仪器最近坏了。2012年和2010年发生的类似故障、相关的服务成本以及缺乏可用部件凸显了对新仪器的需求，特别是考虑到它对这些项目都至关重要。我们的实验室需要所需的设备，因为我们使用的技术的灵敏度要求不能用非放射性方法代替。没有一个功能可靠的ß-counter， NSERC（和其他机构）继续资助博士的研究项目。Goss， Glover和Owttrim将受到致命的阻碍，包括大量HQP学生的研究项目和与这些项目相关的pdf文件。除了成本差异之外，日立AccuFLEX LSC-8000液体闪烁计数器（见所选设备的理由）在样品处理和提供大量持续减少液体放射性氟和塑料生产方面，比Perkin-Elmer机器具有显著优势。总之，AccuFLEX LSC-8000将满足共同申请人的当前要求，并且在可预见的未来也可能被未来的雇员使用。