Liquid Scintillation counter for radiotracer studies

用于放射性示踪剂研究的液体闪烁计数器

• 批准号: RTI-2018-00526
• 负责人: Goss, Gregory
• 金额: $ 3.75万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642186
• 关键词: Liquid; Scintillation; counter; radiotracer; studies

This RTI application is for an automatic ß-counter that is crucially important for three highly successful and NSERC Discovery funded research programs of Professors Dr. Greg Goss, Dr. Chris Glover, and Dr. George Owttrim. Scintillation counting of radioactive ß -particles is one of the most sensitive methods of detection and the use of radioactive tracers is a fundamental component of each of the three-above-mentioned programs in animal or plant physiology. The researchers currently use an old Beckman LS-6500 ß-counter, first purchased in 1993, and this instrument has recently broken down. Similar failures in 2012 and 2010, the associated service costs, and the lack of availability of parts highlight the need for a new instrument, especially given it is essential to each of these programs. We require the requested equipment in our labs because we use techniques whose sensitivity requirements cannot be replaced by non-radioactive methods. Without a functional and reliable ß-counter, the continuance of NSERC (and other agency) funded research programs for Drs. Goss, Glover and Owttrim will be fatally hampered, including the research programs for a large number of HQP students and PDFs associated with these programs. The Hitachi AccuFLEX LSC-8000 liquid scintillation ß- counter (see Justification of equipment selected) provides significant advantages over the Perkin-Elmer machine with respect to sample handling and provision of a substantial and continuous reduction of liquid radioactive fluor and plastic production, in addition to the cost differential. In summary, the AccuFLEX LSC-8000 will meet the current requirements of the co-applicants and also potential use by future hires for the foreseeable future.

此 RTI 应用程序适用于自动 ß-计数器，该计数器对于 Greg Goss 博士、Chris Glover 博士和 George Owttrim 博士教授的三个非常成功且由 NSERC Discovery 资助的研究项目至关重要。放射性β粒子的闪烁计数是最灵敏的检测方法之一，放射性示踪剂的使用是动植物生理学中上述三个程序的基本组成部分。研究人员目前使用一台旧的 Beckman LS-6500 ß-计数器，该仪器首次购买于 1993 年，最近该仪器出现故障。 2012 年和 2010 年发生的类似故障、相关的服务成本以及零件可用性的缺乏凸显了对新仪器的需求，特别是考虑到它对于每个项目都至关重要。我们在实验室中需要所需的设备，因为我们使用的技术的灵敏度要求无法用非放射性方法替代。由于没有功能齐全且可靠的 ß 计数器，NSERC（和其他机构）继续资助 Drs 的研究项目。 Goss、Glover 和 Owttrim 将受到致命的阻碍，包括大量 HQP 学生的研究项目以及与这些项目相关的 PDF。与 Perkin-Elmer 机器相比，Hitachi AccuFLEX LSC-8000 液体闪烁 ß- 计数器（参见所选设备的合理性）除了成本差异外，在样品处理和大幅持续减少液体放射性氟和塑料产量方面具有显着优势。总之，AccuFLEX LSC-8000 将满足共同申请人的当前要求，并在可预见的未来满足未来员工的潜在使用。