Robotic breast cancer surgery

乳腺癌影响八分之一的妇女在他们的生活，是第二大原因， 女性癌症相关死亡理想的治疗方法是在乳腺癌发生期间进行保乳手术。 在早期阶段切除癌症，同时保留乳房的健康部分。沃思电流 切除方法，平均每三名接受乳房保护的妇女中就有一名 由于肿瘤切除不完全，手术需要至少一次额外手术。 重复手术导致术后并发症的风险增加，美容受损， 放射治疗延迟、心理困扰增加以及成本和风险增加 进行第二次全身麻醉重复手术通常会导致全乳房切除术， 这对于期望通过乳房保护进行治愈性治疗的患者来说是一种创伤性经历。 由于早期乳腺癌是不可触及或可见的，外科医生倾向于应用 在靶肿瘤周围有很大的安全裕度，并切除大量健康乳腺 组织.在目前的实践中，高达40%的患者接受保乳手术， 严重的乳房畸形需要手术重建，但超过一半的 这些妇女由于缺乏整形外科能力而得不到治疗。 在这项研究中，我们的目标是开发NaviKnife，一种下一代保乳手术 导航系统，以最小的组织损失实现完整的肿瘤切除。NaviKnife 建立在新型多参数超声成像的基础上， 切除和新的实时代谢组学组织分型，以识别和追踪肿瘤 在简单的机械臂引导下，切除过程中的边界。NaviKnife协助 外科医生在精确的肿瘤切除，并允许切除腔的系统探测 并在必要时指导外科医生有针对性地剃除腔壁 以最小的健康组织损失，从而保证在手术前完全切除肿瘤。 伤口已经闭合。

Breast cancer affects 1 in 8 women during their lives and is the second-leading cause of female cancer related deaths. The ideal treatment is breast-conservation surgery during its early stage to remove the cancer while conserving healthy parts of the breast. Wirth current resection methods, on average, one out of every three women undergoing breastconservation surgery needs at least one additional surgery due incomplete tumor resection. Repeat surgery leads to increased risk of postoperative complications, impaired cosmetics, delayed radiation therapy, increased psychological distress, and increased costs and risks of undergoing a second general anesthesia. Repeat surgery often leads to full mastectomy, which is a traumatic experience for a patient who expected a curative treatment with breastconservation. As early stage breast cancer is not palpable or visible, surgeons tend to apply generous safety margins around the target tumor and remove a great deal of healthy breast tissue. In current practice, up to 40% of patients who undergo breast-conservation surgery experience severe breast deformity that requires surgical reconstruction, but over half of these women do not get treated due to lack reconstructive surgical capacity. In this research, we aim to develop NaviKnife, a next-generation breast conserving surgery navigation system to achieve complete tumor resection with minimal tissue loss. NaviKnife builds on novel multiparametric ultrasound imaging to accurately target the cancer prior to resection and novel real-time metabolomic tissue typing to identify and trace the tumor boundary during resection while guided by a simple robotic arm. NaviKnife assists the surgeon in precise tumor resection and allows for systematic probing of the resection cavity for residual cancer and, if necessary, guides the surgeon in targeted shaving of the cavity wall with minimal loss of healthy tissue, thus guaranteeing complete tumor removal before the wound is closed.