Etudes des mécanismes de l'adaptation et des relations interneuronales au cortex.

在最后一个周期里，我的实验室 调查了两个主题。A)适应对变化的影响 视觉皮质中的首选刺激；我们的发现表明有机会探索 神经元和神经元网络。B)功能界别 形成连接体的神经元之间的关系。本主题建议 对神经元信号进行编码的过程。 我们的研究计划旨在进一步发展 以上创新性的选题，才能了解基础 中枢神经系统的可塑性机制和群体编码动力学。我们建议的节目涉及两个最热门的 主题：连接体的可塑性和动力学。 实验在以下项目上进行 麻醉的动物。电极矩阵被降至大脑皮层。这个 将对以下特定主题进行调查。 A)初始刺激对诱发的反应的影响 通过接下来的刺激。刺激会留下痕迹。 在初始阶段，我们应用两种类型的刺激。第一个条件性短刺激是恒定的，也就是， 表现出相同的性质的，第二个条件 刺激(相同类型)投射出一个可变的属性，例如方向。条件性刺激是 在预定的间隔之后是测试刺激。假设是每个人是如何 条件性刺激影响对测试刺激的反应？

During the last cycle my lab investigated two themes. A) The influence of adaptation on changes of preferred stimulus in visual cortex; our findings point to opportunities to explore plasticity of neurons and neuronal networks. B) The functional relationships between neurons forming a connectome. This topic suggests a process of encoding neuronal signals. Our research program aims to further develop the above innovative topics in order to understand fundamental mechanisms of plasticity and the dynamics of population encoding in the CNS. Our proposed program deals with the two hottest topics: plasticity and dynamics of connectomes. Experiments are carried out on anesthetized animals. Electrode matrices are lowered into the cortex. The following specific subjects will be investigated. A) Influence of an initial stimulus upon responses evoked by a following stimulus. Stimuli leave a trace. In the initial phase we apply two types of stimuli. The first conditioning short stimulus is constant, that is, exhibiting an identical property, the second conditioning stimulus (same type) projects a variable property e.g.orientations. Conditioning stimuli are followed at a predetermined interval by a test stimulus. The hypothesis is how each of the conditioning stimuli affects the responses to the test stimulus?