Production of high value bioproducts

生物质是高价值生物制品和生物活性化合物的丰富来源。这项工作的重点是从富含甘露聚糖、阿拉伯糖和木聚糖的原料中生产高价值的碳水化合物单体和低聚糖，用于动物和人类健康。我们将开发和筛选不同的工艺替代方案，包括高温提取(前处理)、酶解和下游纯化步骤，以生产高纯度的生物制品。将对这些产品进行表征，以评估纯度和组成，包括使用液相色谱-质谱法评估低聚糖的聚合度。不同的产品还将在体外进行评估，以评估它们促进有益细菌生长和抑制病原菌生长的能力，病原菌是人类和动物健康的关键驱动力。有效控制病原菌的产品具有取代抗生素的天然生长促进剂的潜在应用。

Biomass is a rich source of high value bioproducts and bioactive compounds. The focus of this work is upon the production of high value carbohydrate monomers and oligosaccharides from raw materials rich in mannan, arabinan and xylan, for use in animal and human health. We will develop and screen different process alternatives, including high temperature extraction (pretreatment), enzyme hydrolysis, and downstream purification steps to produce high purity bioproducts. These products will be characterized to assess purity and composition, including evaluating the degree of polymerization of the oligosaccharides using liquid chromatography-mass spectrometry. The different products will also be evaluated in vitro to assess their ability to promote the growth of beneficial bacteria, and to inhibit the growth of pathogenic bacteria, key drivers of health for humans and animals. Products that effectively control pathogenic bacteria have potential application as natural growth promoters, displacing antibiotics.