Application of the Solvatochromic Comparison Method to Chromatographic Retention and Selectivity

这个项目是在一般地区的分析和表面 化学和分离科学的子领域。 的 这个实验计划的主旨是阐述 线性溶剂化能关系作为 溶剂对液-液和液-汽的影响 分离过程，这是至关重要的， 分析气液色谱法和分离 工程. 具体来说，基本的化学因素 控制溶质在气体和液体之间的分配 将通过顶空气相色谱法研究相。 已选择待检查的溶质和溶剂， 反映了广泛的溶致变色参数，包括 偶极性，氢键的酸性，碱性和 这些溶剂在分析中的利用程度 色谱法和技术相关分离 流程. 这些研究应该提供一个统一的， 从根本上讲，现代分配均衡 理论和常用的经验关系， 为系统的合理选择提供依据， 所需的分析和工业规模的分离可以 有效和经济地实现。

This project is in the general area of analytical and surface chemistry and in the subfield of separation science. The thrust of this experimental program is the elaboration of linear solvation energy relationships as reliable predictors of the effects of solvent on liquid-liquid and liquid-vapor separation processes that are critically important in analytical gas-liquid chromatography and in separations engineering. Specifically, the fundamental chemical factors controlling the partitioning of solutes between gas and liquid phases will be studied by head space gas chromatography. Solutes and solvents to be examined have been selected to reflect a broad spectrum of solvatochromic parameters including dipolarity, hydrogen bonding acidity, and basicity and the extent of utilization of these solvents in analytical chromatography and technologically relevant separations processes. These studies should provide a unifying and fundamentally sound bridge between modern partition equilibrium theory and commonly used empirical relationships and may provide a basis for the rational selection of systems with which desired analytical and industrial-scale separations could be achieved efficiently and economically.