Application of the Solvatochromic Comparison Method to Chromatographic Retention and Selectivity

溶剂致变色比较法在色谱保留和选择性中的应用

• 批准号: 8616597
• 负责人: Peter Carr
• 金额: $ 46.94万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-01 至 1991-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8616597&HistoricalAwards=false
• 关键词: Application; Solvatochromic; Comparison; Method; Chromatographic

This project is in the general area of analytical and surface chemistry and in the subfield of separation science. The thrust of this experimental program is the elaboration of linear solvation energy relationships as reliable predictors of the effects of solvent on liquid-liquid and liquid-vapor separation processes that are critically important in analytical gas-liquid chromatography and in separations engineering. Specifically, the fundamental chemical factors controlling the partitioning of solutes between gas and liquid phases will be studied by head space gas chromatography. Solutes and solvents to be examined have been selected to reflect a broad spectrum of solvatochromic parameters including dipolarity, hydrogen bonding acidity, and basicity and the extent of utilization of these solvents in analytical chromatography and technologically relevant separations processes. These studies should provide a unifying and fundamentally sound bridge between modern partition equilibrium theory and commonly used empirical relationships and may provide a basis for the rational selection of systems with which desired analytical and industrial-scale separations could be achieved efficiently and economically.

该项目属于分析和表面化学的一般领域，以及分离科学的子领域。这项实验计划的重点是阐述线性溶剂化能关系，作为溶剂对液-液和液-气分离过程的影响的可靠预测，这些过程在分析气-液色谱和分离工程中至关重要。具体地说，将用顶空气相色谱研究控制溶质在气相和液体之间分配的基本化学因素。选择要检查的溶质和溶剂以反映广泛的溶剂变色参数，包括偶极、氢键酸度和碱性，以及这些溶剂在分析色谱和相关技术分离过程中的使用程度。这些研究应该在现代分配均衡理论和常用的经验关系之间提供一座统一的、从根本上可靠的桥梁，并可能为合理选择能够有效和经济地实现所需的分析性和工业规模分离的系统提供基础。