High Voltage Electrophoresis in Capillary Tubes

毛细管高压电泳

• 批准号: 9215320
• 负责人: James Jorgenson
• 金额: $ 41.15万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-08-01 至 1996-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9215320&HistoricalAwards=false
• 关键词: Voltage; Electrophoresis; Capillary; Tubes

This project is in the general area of analytical and surface chemistry and in the subfield of separation science. During the tenure of this forty-month continuing grant, Professor Jorgenson and his students will carry out research in capillary zone electrophoresis (CZE) with specific thrusts in three areas. First, two-dimensional separations protocols involving hybrid liquid chromatography - cze techniques will be explored; second, new post-column reaction/fluorescence detection protocols will be developed to expand the versatility of cze-based analytical techniques; and third, a new approach to high resolution cze which utilizes electroosmotically counterbalanced electrophoresis (ECE) will be developed and refined. This project builds upon research carried out by Professor Jorgenson and his students under NSF grant CHE-8912926. %%% The successful attainment of the goals of this project will provide strongly enabling analytical tools that will be applicable to a broad spectrum of chemical, environmental, and biological problems.

这个项目是在一般地区的分析和表面 化学和分离科学的子领域。 期间 这40个月的持续资助，教授乔根森 他的学生将在毛细管区进行研究 电泳（CZE）在三个领域的具体推力。 首先，二维分离协议涉及混合 将探索液相色谱-CZE技术;第二， 新的柱后反应/荧光检测方案将 为扩大cze分析的多功能性而开发的 技术;第三，高分辨率cze的新方法， 利用电平衡电泳（ECE） 将得到发展和完善。 这个项目建立在研究的基础上 由乔根森教授和他的学生在国家科学基金会下进行的 授权CHE-8912926。 %%% 该项目目标的成功实现将 提供强有力的分析工具， 适用于广泛的化学、环境和 生物问题。