Purchase of a 500 MHz NMR Spectrometer

购买 500 MHz 核磁共振波谱仪

• 批准号: 9523034
• 负责人: John Birks
• 金额: $ 31.29万
• 依托单位: University of Colorado at Boulder
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-12-01 至 1997-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9523034&HistoricalAwards=false
• 关键词: Purchase; 500; MHz; NMR; Spectrometer

This award from the Chemistry Research Instrumentation and Facilities Program will help the Department of Chemistry at the University of Colorado--Boulder acquire a 500 MHz NMR Spectrometer. The research activities to be supported include: (1) development of stereoselective synthetic methods and sequential reactions schemes; (2) investigations of adriamycin-mediated DNA cross-links; (3) the development of stereoselective and catalytic asymmetric methods for organic synthesis; (4) synthetic and bioorganic studies of DNA and RNA; (5) structure determination of proteins; (6) the total synthesis and bioorganic studies of natural products and complex carbohydrates. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers and catalysis, and in biology.

这份来自化学研究仪器和设施项目的合同将帮助科罗拉多大学博尔德分校化学系获得一台500 MHz核磁共振光谱仪。支持的研究活动包括：(1)发展立体选择性合成方法和顺序反应方案；(2)阿霉素介导的DNA交联研究；(3)立体选择性和催化不对称有机合成方法的发展；(4) DNA和RNA的合成和生物有机研究；(5)蛋白质结构测定；(6)天然产物和复合碳水化合物的全合成和生物有机研究。核磁共振（NMR）波谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。从这些核磁共振研究的结果是有用的领域，如聚合物和催化，并在生物学。