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Engineering Pore Forming Proteins as machines for the delivery of proteins and nanoparticles into cells

Engineering Pore Forming Proteins as machines for the delivery of proteins and nanoparticles into cells
工程造孔蛋白作为将蛋白质和纳米颗粒输送到细胞中的机器
批准号:
FS100100073
负责人:
Prof James Whisstock
金额:
$59.65万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Super Science Fellowships
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2015-12-31

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中文摘要
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英文摘要
This cross disciplinary project will revolutionise our ability to build pore forming nano-machines that specifically deliver complex macromolecules to the cell cytoplasm. The ability to efficiently deliver molecules such as antibodies and nanoparticles to the correct cell population will have enormous therapeutic application. Further, such delivery devices will have revolutionary technological potential as commercially relevant research tools.
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The structural basis for MPEG1 mediated assembly of immune complexes
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2022
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Controlling the function of pore forming perforin-like proteins in immune mediated disease
  • 批准号:
    nhmrc : GNT1154184
  • 项目类别:
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  • 资助金额:
    $88.83万
  • 财政年份:
    2019
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Molecular basis for conjugative transfer of antibiotic resistance genes in Gram positive pathogens
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  • 项目类别:
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    $60.03万
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海外基金