Structural and functional studies on prokaryote serpins
Structural and functional studies on prokaryote serpins
批准号:
DP0663860
负责人:
Prof James Whisstock
金额:
$20.34万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2006
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2006-01-03 至 2008-12-31
中文摘要
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英文摘要
Proteins are the machines of life, many of which undergo complex movements to achieve function. The basic research described in this proposal will result in major outcomes in understanding how proteins fold, undergo complex changes in conformation, and misfold to dysfunctional states. As a result, the study will contribute fundamental knowledge that will underpin research in the fields of structural biology, protein design and protein folding. Through providing insight into protein misfolding, the work will will contribute to our understanding of degenerative misfolding pathologies that affect the ageing population and thus targets the 'ageing well ageing productively' priority goal.
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依托单位:
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依托单位:
国内基金
海外基金
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