The mechanism of conjugative transfer of antibiotic resistance genes in Gram positive pathogens
The mechanism of conjugative transfer of antibiotic resistance genes in Gram positive pathogens
批准号:
nhmrc : 1048676
负责人:
Prof James Whisstock
金额:
$41.91万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
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英文摘要
Antibiotic resistant bacteria pose a serious threat to the health of Australians. We will determine how antibiotic resistance genes spread from one bacterium to another. Using a disease-causing bacterium as model we will determine the mechanism by which this gene transfer process occurs and the structure and function of the key components. The result will be major advances in our understanding of the evolution of the antibiotic resistant bacteria that are major causes of human disease.
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ARC Centre of Excellence in Advanced Molecular Imaging
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批准号:CE140100011
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财政年份:2014
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依托单位:
Proteolytic systems in Health and Disease
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依托单位:
Proteolytic systems in Health and Disease
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资助金额:$57.57万
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依托单位:
Understanding how perforin forms pores: the role of calcium and lipids.
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批准号:nhmrc : 1042858
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The structural basis for plasminogen activation
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A centre for structural cryo-electron microscopy
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依托单位:
Engineering Pore Forming Proteins as machines for the delivery of proteins and nanoparticles into cells
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依托单位:
Membrane attack complex/perforin-like proteins in developmental and neurobiology
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依托单位:
Structural and Functional studies on Membrane Attack Complex / Perforin-like proteins
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依托单位:
Membrane Attack Complex / Perforin like proteins in Defence, Attack and Developmental Biology
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 436623
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依托单位:
Structural and functional studies on prokaryote serpins
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Establishing a high-throughput Protein Production Unit
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依托单位:
Development of a collaborative environment for high throughput biology discovery pipelines.
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Searching for novel protein domains: A bioinformatic analysis of whole proteomes
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依托单位:
国内基金
海外基金
万古霉素耐药肠球菌非信息素反应型接合性质粒水平转移机制
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批准号:81171612
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项目类别:面上项目
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资助金额:58.0万元
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批准年份:2011
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负责人:郑波
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依托单位: