Understanding how perforin forms pores: the role of calcium and lipids.

了解穿孔素如何形成毛孔：钙和脂质的作用。

• 批准号: nhmrc : 1042858
• 负责人: Prof James Whisstock
• 金额: $ 53.2万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-perforin-forms-calcium-lipids/111518
• 关键词: Understanding; how; perforin; forms; pores

This grant aims to study perforin, a key part of the mammalian immune system. The work will facilitate the development of perforin inhibitors. It is anticipated that these data will be of utility in developing first in class drugs to improve the success of bone marrow transplantation.

该基金旨在研究穿孔素，这是哺乳动物免疫系统的关键部分。该工作将促进穿孔素抑制剂的开发。预计这些数据将有助于开发一流的药物，以提高骨髓移植的成功率。