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Understanding how perforin forms pores: the role of calcium and lipids.

Understanding how perforin forms pores: the role of calcium and lipids.
了解穿孔素如何形成毛孔:钙和脂质的作用。
批准号:
nhmrc : 1042858
负责人:
Prof James Whisstock
金额:
$53.2万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31

项目摘要

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中文摘要
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英文摘要
This grant aims to study perforin, a key part of the mammalian immune system. The work will facilitate the development of perforin inhibitors. It is anticipated that these data will be of utility in developing first in class drugs to improve the success of bone marrow transplantation.
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会议论文
The structural basis for MPEG1 mediated assembly of immune complexes
  • 批准号:
    DP220103197
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $39.67万
  • 财政年份:
    2022
  • 负责人:
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An in situ structural study of Drosophila embryonic patterning
  • 批准号:
    FL180100019
  • 项目类别:
    Australian Laureate Fellowships
  • 资助金额:
    $200.23万
  • 财政年份:
    2019
  • 负责人:
    Prof James Whisstock
  • 依托单位:
Controlling the function of pore forming perforin-like proteins in immune mediated disease
  • 批准号:
    nhmrc : GNT1154184
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $88.83万
  • 财政年份:
    2019
  • 负责人:
    Prof James Whisstock
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Molecular basis for conjugative transfer of antibiotic resistance genes in Gram positive pathogens
  • 批准号:
    nhmrc : 1104502
  • 项目类别:
    Project Grants
  • 资助金额:
    $60.03万
  • 财政年份:
    2016
  • 负责人:
    Prof James Whisstock
  • 依托单位:
海外基金