Upgrade of Ohio State University Chemistry Department NMR Facility

化学研究仪器和设施(CRIF)计划和多学科活动办公室(OMA)颁发的这一奖项将帮助俄亥俄州立大学化学系获得400 MHz核磁共振(核磁共振)光谱仪以及250 MHz和300 MHz核磁共振控制台。该设备将加强以下领域的研究：(1)用于不对称催化的手性金属络合物，(2)复杂碳水化合物体系的构象分析，(3)特殊分子体系的构建，(4)卡宾重排的激活势垒，(5)穿孔素介导的细胞溶解，(6)用于不对称催化的树枝状大分子，(7)高势铁蛋白，以及(8)特定碳离子物种的结构和动力学行为。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这些核磁共振研究的结果在聚合物、催化和生物学等领域都是有用的。

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Office of Multidisciplinary Activities (OMA) will assist the Department of Chemistry at Ohio State University to acquire a 400 MHz nuclear magnetic resonance (NMR) spectrometer and 250 MHz and 300 MHz NMR consoles. This equipment will enhance research in a number of areas such as the following: (1) chiral metal complexes for asymmetric catalysis, (2) conformational analysis of complex carbohydrate systems, (3) construction of unusual molecular systems, (4) activation barriers for carbene rearrangements, (5) perforin-mediated cytolysis (6) catalytic dendrimers for asymmetric catalysis, (7) high potential iron proteins, and (8) structure and dynamic behavior of selected carbanionic species. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers, catalysis, and in biology.