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A New Capillary Sequencer for the Evolutionary Genetics Core Facility at Cornell University

康奈尔大学进化遗传学核心设施的新型毛细管测序仪

基本信息

批准号：
0400433
负责人：
Kelly Zamudio
金额：
$ 12.37万
依托单位：
Cornell University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2004
资助国家：
美国
起止时间：
2004-05-01 至 2006-04-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=0400433&HistoricalAwards=false
关键词：
New Capillary Sequencer Evolutionary Genetics

项目摘要

This award provides partial support for purchase of a modern capillary DNA sequencer and supporting computer equipment for the Cornell Evolutionary Genetics Core Facility (EGCF). The instrument will be equipped for both sequence determination and fragment analysis. The facility supports research by evolutionary biologists, population biologists, behavioral ecologists, and systematists. Research in these areas increasingly depends on variation in the DNA sequences of individual organisms to provide information on mating systems, population structure, genealogy, and phylogeny. Automated DNA sequencing and genotyping are critical to studies employing such variation. The facility is used by 19 faculty in seven departments across the Cornell campus, and contributes significantly to their research programs and the educational experience of their graduate and undergraduate students. Their research programs address various aspects of biodiversity, including the origins and maintenance of plant and animal diversity, and the management of taxa of conservation concern or of economic importance. Aside from the impact of each individual user, the facility plays an important role in teaching and training on the Cornell campus. The new equipment will increase throughput and data quality for all users, improve the training of students, and catalyze interactions among evolutionary biologists and ecologists with diverse taxonomic and disciplinary interests.

该奖项为康奈尔进化遗传学核心设施（EGCF）提供了购买现代毛细管DNA测序仪和支持计算机设备的部分支持。该仪器将配备用于序列测定和片段分析。该设施支持进化生物学家、种群生物学家、行为生态学家和系统学家的研究。这些领域的研究越来越依赖于个体生物DNA序列的变异，以提供有关交配系统、种群结构、谱系和系统发育的信息。自动DNA测序和基因分型对利用这种变异进行研究至关重要。该设施由康奈尔大学七个系的19名教师使用，对他们的研究项目和研究生和本科生的教育经历做出了重大贡献。他们的研究项目涉及生物多样性的各个方面，包括植物和动物多样性的起源和维护，以及保护关注或经济重要性的分类群的管理。除了对每个用户的影响外，该设施在康奈尔大学校园的教学和培训中起着重要作用。新设备将提高所有用户的吞吐量和数据质量，改善学生的培训，并促进具有不同分类和学科兴趣的进化生物学家和生态学家之间的互动。