Acquisition of a 500-MHz NMR Spectrometer

购买 500 MHz 核磁共振波谱仪

• 批准号: 0619254
• 负责人: Franklin Schultz
• 金额: $ 51.65万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-15 至 2009-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619254&HistoricalAwards=false
• 关键词: Acquisition; 500; MHz; NMR; Spectrometer

With support from the Major Research Instrumentation (MRI) Acquisition Program, the Department of Chemistry and Chemical Biology at Indiana University-Purdue University at Indianapolis (IUPUI) will acquire a 500 MHz NMR spectrometer. The spectrometer will be used in various research investigations involving natural and non-natural products, advanced polymers for biomedical applications, electron transfer and spin-crossover reactions, protein tyrosine phosphatases, metallopeptides that bind to DNA, synthesis of peptidomimetics, stereoselective boron alkylation studies, structural characterization of sphingolipids, and biosynthetic pathways to polyacetylenes. Nuclear Magnetic Resonance (NMR) Spectroscopy is the most widely used tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances and to provide information on the arrangement and connectivity of atoms in molecules. Dynamical information is obtained providing insight on the motions of molecules. This award will provide essential analytical capabilities to faculty and students at (IUPUI). Creation and implementation of a NMR certification program for student users is planned to enhance the educational value of the new instrument.

在主要研究仪器（MRI）采购计划的支持下，印第安纳州普渡大学印第安纳波利斯分校（IUPUI）的化学和化学生物学系将获得一台500 MHz NMR光谱仪。 光谱仪将用于各种研究调查，涉及天然和非天然产品，生物医学应用的先进聚合物，电子转移和自旋交叉反应，蛋白质酪氨酸磷酸酶，与DNA结合的金属肽，拟肽的合成，立体选择性硼烷基化研究，鞘脂的结构表征，以及聚乙炔的生物合成途径。 核磁共振（NMR）光谱是化学家用于阐明分子结构的最广泛使用的工具。 它用于识别未知物质，并提供有关分子中原子排列和连接的信息。 获得动力学信息，提供对分子运动的洞察。 该奖项将提供必要的分析能力，教师和学生在（IUPUI）。 计划为学生用户创建和实施NMR认证计划，以提高新仪器的教育价值。