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MRI: Acquisition of a 500 MHz Nuclear Magnetic Resonance Spectrometer for Research and Training at the University of Arizona

MRI：购买 500 MHz 核磁共振波谱仪用于亚利桑那大学的研究和培训

基本信息

批准号：
1920234
负责人：
Jon Njardarson
金额：
$ 50.08万
依托单位：
University of Arizona
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-01 至 2022-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1920234&HistoricalAwards=false
关键词：
MRI Acquisition 500 MHz Nuclear

项目摘要

This award is funded by the Major Research Instrumentation (MRI) and Chemical Instrumentation (CRIF) programs. Professor Jon Njardarson from University of Arizona and colleagues Wei Wang, Jeffrey Pyun, Douglas Loy and Elisa Tomat have acquired a 500 MHz NMR spectrometer. In general, NMR spectroscopy is one of the basic tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is an essential tool for chemists who are carrying out frontier research. A typical use by a chemist is to analyze the mixture from a reaction to determine the products. For example investigations to improve materials used in battery electrodes to increase their efficiency will involve following the products by varying the starting materials in a chemical reaction. The spectrometer is used in laboratory courses to train undergraduate students in this powerful tool. A sizable cohort are from underrepresented and underserved groups. The award is aimed at enhancing research and education at all levels. A variety of research projects are being investigated. One project explores new synthetic methods used to prepare natural products. Another investigation probes the engineering of ligand-based redox chemistry in metal complexes of linear oligopyrroles. Sustainable polymer chemistry through utilization of waste sulfur to afford a new class of sulfur-based polymers is being studied. Metallopolymer electrocatalysts for hydrogen production are the focus of an investigation. Pioneering investigations to construct nano-engineered, hybrid organic-inorganic materials based on organically bridged polysilsesquioxanes is a current on-going study.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器（MRI）和化学仪器（CRIF）计划资助。来自亚利桑那大学的Jon Njardarson教授和他的同事Wei Wang、Jeffrey Pyun、道格拉斯Loy和Elisa Tomat获得了一台500 MHz的NMR光谱仪。一般来说，NMR光谱是化学家用于阐明分子结构的基本工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的工具。化学家的一个典型用途是分析反应的混合物以确定产物。例如，改进电池电极中使用的材料以提高其效率的研究将涉及通过改变化学反应中的起始材料来跟踪产物。光谱仪用于实验室课程，以培训本科生使用这一强大的工具。一个相当大的群体来自代表性不足和服务不足的群体。该奖项旨在加强各级的研究和教育。正在研究各种研究项目。其中一个项目探索用于制备天然产品的新合成方法。另一项研究探讨了线性低聚吡咯金属配合物中基于配体的氧化还原化学工程。目前正在研究通过利用废硫磺来提供一类新的硫基聚合物的可持续高分子化学。金属聚合物电催化制氢是目前研究的热点。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Albumin Conjugates of Thiosemicarbazone and Imidazole-2-thione Prochelators: Iron Coordination and Antiproliferative Activity.

DOI：
10.1002/cmdc.202100278
发表时间：
2021-09-16
期刊：
ChemMedChem
影响因子：
3.4
作者：
Sung YS;Wu W;Ewbank MA;Utterback RD;Marty MT;Tomat E
通讯作者：
Tomat E

Multicenter interactions and ligand field effects in platinum( ii ) tripyrrindione radicals

铂( ii )三吡啶二酮自由基的多中心相互作用和配体场效应

DOI：
10.1039/d3dt00894k
发表时间：
2023
期刊：
Dalton Transactions
影响因子：
4
作者：
Tomat, Elisa;Curtis, Clayton J.;Astashkin, Andrei V.;Conradie, Jeanet;Ghosh, Abhik
通讯作者：
Ghosh, Abhik

Anionic Amino-Cope Rearrangement Cascade Synthesis of 2,4-Substituted Benzoate Esters from Acyclic Building Blocks

由无环结构单元阴离子氨基-Cope重排级联合成 2,4-取代苯甲酸酯

DOI：
10.1021/acs.orglett.2c03134
发表时间：
2022
期刊：
Organic letters
影响因子：
5.2
作者：
Qureshi, M. Haziq;Njardarson, Jon T.
通讯作者：
Njardarson, Jon T.

Oxidative Route to Indoles via Intramolecular Amino-Hydroxylation of o -Allenyl Anilines

通过邻联烯基苯胺的分子内氨基羟基化氧化为吲哚的路线

DOI：
10.1021/acs.joc.1c01379
发表时间：
2021
期刊：
The Journal of Organic Chemistry
影响因子：
0
作者：
Lauta, Nicholas R.;Williams, Ryan E.;Smith, David T.;Kumirov, Vlad K.;Njardarson, Jon T.
通讯作者：
Njardarson, Jon T.

Photoredox Asymmetric Nucleophilic Dearomatization of Indoles with Neutral Radicals

吲哚与中性自由基的光氧化还原不对称亲核脱芳构化