MRI: Aquisition of a Dip Pen Nanolithography System for Surface Nanofunctionalization

MRI：获取用于表面纳米功能化的浸笔纳米光刻系统

• 批准号: 0619355
• 负责人: Matthew Libera
• 金额: $ 16.79万
• 依托单位: Stevens Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619355&HistoricalAwards=false
• 关键词: MRI; Aquisition; Dip; Pen; Nanolithography

Technical AbstractThe Stevens Institute of Technology will acquire a dip pen nanolithography (DPN) system. With it, Stevens and its collaborators at area universities will create a novel resource for high-resolution functionalization of surfaces. DPN is a new approach, which is uniquely suited for chemically modifying surfaces at length scales as small as 10 nm. Because of its ability to precisely position its tip, DPN can modulate such chemical modifications in diverse user-defined patterns to enhance a broad range of different research projects. A group of five research-active scientists from three different Northern New Jersey institutions will use the DPN system to substantially enhance a set of forward-looking projects that include: development of nanohydrogel-based protein nanoarrays; coherent surface-enhanced Raman spectroscopy using directed deposition of Ag and Au nanoparticle arrays; and stem cell differentiation on biochemically nanopatterned surfaces. In addition to these research initiatives, the DPN system will also anchor several new educational and outreach activities. For example, new concepts of surface nanofunctionalization will be incorporated into a series of courses offered at Stevens and at the nearby New Jersey Institute of Technology. Forward-looking ideas of nanotechnology will also be introduced into ongoing summer outreach programs to underprivileged high-school students. This effort, executed in collaboration with the American Chemical Society SEED program, will encourage these young people to pursue college opportunities in science and engineering. Lay AbstractDip-pen nanolithography (DPN) is among the newest and most advanced scientific tools for controlling how the surfaces of materials interact with their surroundings. DPN can create patterns that are almost 1000 times smaller than those in state-of-the-art electronic devices like advanced computer chips. Furthermore, DPN can deposit as little as a few molecules at each point in the surface pattern, and this capability gives scientists and engineers impressive new control over chemical reactions that occur at very specific points on a surface. We will use DPN in research projects to learn how individual cells behave when they stick to a surface, to develop new sensors that can detect trace quantities of harmful chemicals, and to build new tools for biomedical research and clinical diagnostics. We will also use the DPN system as a new part of a very successful program called Project SEED that provides summer internships to underpriviledged high-school students. We expect that introducing these students to some of the exciting opportunities associated with nanotechnology will help encourage them to pursue a college education and work towards careers in science and engineering.

技术摘要史蒂文斯技术学院将获得倾笔纳米石刻（DPN）系统。 有了它，史蒂文斯及其在地区大学的合作者将创建一个新的资源，以用于表面的高分辨率功能化。 DPN是一种新方法，它非常适合于在长达10 nm的长度尺度上的化学修饰表面。 由于其能够精确定位其尖端，DPN可以在多种用户定义的模式中调节这种化学修改，以增强广泛的不同研究项目。 来自新泽西州北部三个不同机构的五个研究活性科学家组成的小组将使用DPN系统实质上增强了一组前瞻性项目，其中包括：开发基于纳米羟基的蛋白质纳米阵列；使用Ag和Au纳米颗粒阵列的定向沉积，相干表面增强的拉曼光谱；以及生物化学上纳米平均表面的干细胞分化。 除了这些研究计划外，DPN系统还将奠定一些新的教育和外展活动。 例如，将表面纳米功能化的新概念纳入史蒂文斯和附近新泽西技术学院提供的一系列课程中。 纳米技术的前瞻性思想也将引入正在进行的夏季外展计划中，以向贫困的高中生学生。 与美国化学学会种子计划合作执行的这项努力将鼓励这些年轻人在科学和工程方面寻求大学机会。 Lay AbstractDip-Pen纳米光刻（DPN）是控制材料表面如何与周围环境相互作用的最新，最先进的科学工具之一。 DPN可以创建比最先进的电子设备（如高级计算机芯片）小的1000倍的图案。 此外，DPN可以在表面模式中的每个点沉积几个分子，并且该能力使科学家和工程师对在表面上非常特定点发生的化学反应进行了令人印象深刻的新控制。 我们将在研究项目中使用DPN来了解单个细胞在表面上的表现，开发可以检测微量量有害化学物质的新传感器，并为生物医学研究和临床诊断的新工具构建新工具。 我们还将使用DPN系统作为一个非常成功的计划的新部分，称为Project Seed，该计划为贫困的高中生提供暑期实习。 我们希望将这些学生介绍与纳米技术相关的一些激动人心的机会，这将有助于鼓励他们从事大学教育，并从事科学和工程学的职业。