MRI: Acquisition of a 500 MHz NMR Spectrometer for Teaching and Research

MRI：购买 500 MHz NMR 波谱仪用于教学和研究

• 批准号: 1126005
• 负责人: Rastislav Levicky
• 金额: $ 39.25万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1126005&HistoricalAwards=false
• 关键词: MRI; Acquisition; 500; MHz; NMR

1126005GrossFunds are requested to purchase a 500 MHz NMR to replace the very old and Bruker DPX 300 MHz NMR at Polytechnic Institute of New York University?s (NYU-POLY). The instrument will have two radio-frequency channels, pulsed-field gradients, variable-temperature capability, two solution probes with automatic tune and match, and an autosampler. The current NMR needs replacement for the following reasons: i) it is very old, ii) its capabilities are severely limited, iii) the need for greater dispersion and sensitivity provided by higher field strength. The current NMR has no pulse field gradients and no ability to shape radio-frequency pulse and, as such, it cannot perform modern 2D experiments or modern solvent suppression echniques.Contemporary NMR methods are essential to research at NYU-POLY. Our current instrument is so old that spare parts are no longer available and the instrument will soon cease to function. Furthermore, its sensitivity is poor and the requested NMR will provide five times greater sensitivity. The proposed 500 MHz NMR with high dispersion and ability to perform modern 2D experiments will be an essential research tool to the proposal PI, Co-PI?s, their students (in total 9 High School, 18 undergrad, 21 MS, 27 Ph.D. and 5.5 postdoctoral fellows), and other faculty in the Polymer Research Institute (PRI), Departments of Chemical and Biological Sciences, Chemical and Biological Engineering, and Bioengineering.

1126005 GrossFunds被要求购买一台500 MHz NMR，以取代纽约大学理工学院非常旧的和布鲁克DPX 300 MHz NMR？s（NYU-POLY）。该仪器将有两个射频通道，脉冲场梯度，可变温度能力，两个自动调谐和匹配的溶液探针，以及一个自动进样器。目前的NMR需要更换，原因如下：i）它非常陈旧，ii）其能力受到严重限制，iii）需要由更高的场强提供更大的色散和灵敏度。目前的核磁共振没有脉冲场梯度，也没有形成射频脉冲的能力，因此，它不能进行现代二维实验或现代溶剂抑制技术。现代核磁共振方法对纽约大学POLY的研究至关重要。我们现有的仪器太旧，没有备件，仪器很快就会停止工作。此外，它的灵敏度很差，要求的NMR将提供五倍的灵敏度。拟议的500 MHz NMR具有高色散和执行现代2D实验的能力将是一个必不可少的研究工具，建议PI，合作PI？他们的学生（共9名高中生，18名本科生，21名硕士生，27名博士生）。和5.5名博士后研究员），以及聚合物研究所（PRI），化学和生物科学系，化学和生物工程系以及生物工程系的其他教员。