MRI: Acquisition of High Sensitivity 500 MHz NMR for the University of Oregon CAMCOR NMR Facility

MRI：为俄勒冈大学 CAMCOR NMR 设施购置高灵敏度 500 MHz NMR

• 批准号: 1427987
• 负责人: Michael Haley
• 金额: $ 42.45万
• 依托单位: University of Oregon Eugene
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2017-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1427987&HistoricalAwards=false
• 关键词: MRI; Acquisition; Sensitivity; 500; MHz

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor Michael Haley from the University of Oregon Eugene and colleague S. Michael Strain will acquire a 500 MHz NMR spectrometer equipped with a broad band observe multinuclear broadband cryoprobe with automated tuning. These capabilities will be used for characterizing complex and/or low-solubility synthetic materials ranging from compounds designed for organic electronic applications to RNA biopolymers and "designed" nanoparticles. The spectrometer will be placed in the Center for Advanced Materials Characterization in Oregon (CAMCOR). In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research by postdoctoral, graduate and undergraduate students at the University of Oregon Eugene and will also impact outreach activities involving K-12 programs that target schools with a predominantly minority populations as well as industrial collaborators. The resource will be available to students and collaborators at the University of Oregon Eugene, Oregon State University, Portland State University, and Lane Community College.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) synthesizing Fe-phosphine complexes for use as liquid-phase absorbents in the purification of natural gas; (b) synthesizing precision engineered nanoparticles; (c) using indenofluorene and indenofluorenediones as electron-accepting scaffolds for organic electronics; (d) studying nanoscale aqueous M13 clusters and molecular probes for small molecule/ion recognition; (e) self-assembling ligands for transition metal catalysts and chemical tools for studying biological hydrogen sulfide; and (f) using Pt(II) reagents for RNA biochemistry.

在重大研究仪器计划(MRI)的这一奖项和化学研究仪器计划(CRIF)的支持下，来自俄勒冈大学尤金大学的Michael Haley教授和他的同事S.Michael Strand将获得一台500 MHz核磁共振光谱仪，该光谱仪配备了一个可自动调谐的宽带观察多核低温探头。这些能力将用于表征复杂和/或低溶解度的合成材料，从为有机电子应用而设计的化合物到RNA生物聚合物和“设计”的纳米颗粒。光谱仪将放置在俄勒冈州先进材料表征中心(CAMCOR)。总的来说，核磁共振波谱是化学家用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对合成有机/无机化学、材料化学和生物化学产生影响。该工具将是俄勒冈大学尤金分校博士后、研究生和本科生教学和研究的组成部分，还将影响涉及K-12项目的外联活动，这些项目针对的是以少数族裔为主的学校以及行业合作者。该资源将提供给俄勒冈大学尤金分校、俄勒冈州立大学、波特兰州立大学和莱恩社区学院的学生和合作者。该奖项旨在加强所有层面的研究和教育，特别是在以下领域：(A)合成用作天然气净化的液态吸附剂的铁膦络合物；(B)合成精密工程纳米颗粒；(C)使用吲哚和吲哚荧二酮作为有机电子学的电子接受支架；(D)研究纳米级水M13团簇和分子探针，用于小分子/离子识别；(E)用于过渡金属催化剂的自组装配体和用于研究生物硫化氢的化学工具；和(F)将铂(II)试剂用于RNA生物化学。