MRI: Acquisition of High Sensitivity 500 MHz NMR for the University of Oregon CAMCOR NMR Facility

MRI：为俄勒冈大学 CAMCOR NMR 设施购置高灵敏度 500 MHz NMR

• 批准号: 1427987
• 负责人: Michael Haley
• 金额: $ 42.45万
• 依托单位: University of Oregon Eugene
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2017-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1427987&HistoricalAwards=false
• 关键词: MRI; Acquisition; Sensitivity; 500; MHz

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor Michael Haley from the University of Oregon Eugene and colleague S. Michael Strain will acquire a 500 MHz NMR spectrometer equipped with a broad band observe multinuclear broadband cryoprobe with automated tuning. These capabilities will be used for characterizing complex and/or low-solubility synthetic materials ranging from compounds designed for organic electronic applications to RNA biopolymers and "designed" nanoparticles. The spectrometer will be placed in the Center for Advanced Materials Characterization in Oregon (CAMCOR). In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research by postdoctoral, graduate and undergraduate students at the University of Oregon Eugene and will also impact outreach activities involving K-12 programs that target schools with a predominantly minority populations as well as industrial collaborators. The resource will be available to students and collaborators at the University of Oregon Eugene, Oregon State University, Portland State University, and Lane Community College.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) synthesizing Fe-phosphine complexes for use as liquid-phase absorbents in the purification of natural gas; (b) synthesizing precision engineered nanoparticles; (c) using indenofluorene and indenofluorenediones as electron-accepting scaffolds for organic electronics; (d) studying nanoscale aqueous M13 clusters and molecular probes for small molecule/ion recognition; (e) self-assembling ligands for transition metal catalysts and chemical tools for studying biological hydrogen sulfide; and (f) using Pt(II) reagents for RNA biochemistry.

在主要研究仪器计划（MRI）的奖励和化学研究仪器计划（CRIF）的支持下，来自俄勒冈州大学的Michael Haley教授尤金和同事S. Michael Strain将获得一台500 MHz NMR光谱仪，该光谱仪配备了一个宽带观察多核宽带冷冻探针，可自动调谐。这些能力将用于表征复杂和/或低溶解度的合成材料，从为有机电子应用设计的化合物到RNA生物聚合物和“设计”的纳米颗粒。光谱仪将被放置在俄勒冈州的先进材料表征中心（CAMCOR）。一般来说，核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学、材料化学和生物化学产生影响。该仪器将是教学的一个组成部分，以及研究的博士后，研究生和本科生在俄勒冈州尤金的大学，也将影响涉及K-12计划，目标学校主要是少数民族人口以及工业合作者的推广活动。该资源将提供给俄勒冈州尤金大学、俄勒冈州州立大学、波特兰州立大学和莱恩社区学院的学生和合作者。该奖项旨在加强各级研究和教育，特别是在以下领域：（a）合成铁膦络合物，用作天然气净化中的液相吸收剂;（B）合成精密工程纳米颗粒;（c）合成纳米颗粒;（d）合成纳米颗粒。（c）使用茚并芴和茚并芴二酮作为有机电子学的电子接受支架;（d）研究纳米级含水M13团簇和用于小分子/离子识别的分子探针;（e）过渡金属催化剂的自组装配体和用于研究生物硫化氢的化学工具;以及（f）使用Pt（II）试剂进行RNA生物化学。