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PFI-TT: Development of Easy-to-Use Affordable Sensors for Rapid Detection of Environmental Pollutants

PFI-TT：开发易于使用且经济实惠的传感器，用于快速检测环境污染物

基本信息

批准号：
2141017
负责人：
Emanuela Andreescu
金额：
$ 25万
依托单位：
Clarkson University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2022
资助国家：
美国
起止时间：
2022-01-01 至 2024-12-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2141017&HistoricalAwards=false
关键词：
PFI TT Development Easy Use

项目摘要

The broader impact/commercial potential of this Partnerships for Innovation - Technology Translation (PFI-TT) project is to create a low cost technology to detect, screen and quantify per- and polyfluoroalkyl substances (PFAS), an emerging group of environmental pollutants. PFAS are used in many commercial products and applications and have recently been identified as posing significant threats to human health. The proposed technology addresses the environmental testing needs for low cost detection of PFAS by providing the tools needed to better estimate their distribution, exposure, and treatment efficacy. Through partnerships with industry and established advanced technology and innovation centers, this PFI-TT project seeks to establish the performance, testing and manufacturing of a portable device for field analysis. Other activities include the development of a go-to-market strategy, customer discovery, and validation. The technology developed in this project may provide broader adoption by non-expert users, providing social and economic benefits in the environmental sector. The team will work with the Shipley Center for Innovation and the Graduate School at Clarkson University to develop new curriculum and workforce development modules covering laboratory management, team science and intellectual property, and teamwork and collaboration in the workplace. The team will also organize workshops to train undergraduate and graduate students in innovation and entrepreneurship. The proposed project seeks to advance the development of programmable receptors that have the capability to react with PFAS through electrostatic and fluoride-specific interactions, generating concentration-dependent changes in the status of the receptors, thus enabling their measurement by low cost spectroscopic and electrochemical techniques. Fundamental investigations of the interaction of PFAS with the receptors have led to the discovery of unique candidates that change their optical and electrochemical properties with the type, length, structure, and concentration of PFAS. This PFI-TT project may develop protocols and a manufacturing processes to create portable sensors and establish performance for quantitative detection of PFAS. The availability and commercialization of easy-to-use affordable PFAS sensors have the potential result in more effective, broadly available, and lower-cost analyses that may translate into improved monitoring of environmental pollution.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这一创新-技术转化伙伴关系项目的更广泛影响/商业潜力是创造一种低成本技术，用于检测、筛选和量化全氟烷基和多氟烷基物质（PFAS），这是一组新出现的环境污染物。 PFAS用于许多商业产品和应用，最近被确定为对人类健康构成重大威胁。所提出的技术通过提供更好地估计其分布、暴露和治疗效果所需的工具，解决了PFAS低成本检测的环境测试需求。通过与行业和成熟的先进技术和创新中心的合作，PFI-TT项目旨在建立现场分析便携式设备的性能，测试和制造。其他活动包括开发进入市场战略、客户发现和验证。本项目开发的技术可为非专家用户提供更广泛的采用，为环境部门带来社会和经济效益。该团队将与希普利创新中心和克拉克森大学研究生院合作，开发新的课程和劳动力发展模块，涵盖实验室管理、团队科学和知识产权，以及工作场所的团队合作和协作。该团队还将组织研讨会，培训本科生和研究生的创新和创业精神。拟议项目旨在推进可编程受体的开发，这些受体能够通过静电和氟化物特异性相互作用与PFAS反应，产生受体状态的浓度依赖性变化，从而使其能够通过低成本光谱和电化学技术进行测量。对PFAS与受体相互作用的基础研究发现了独特的候选物，这些候选物随着PFAS的类型、长度、结构和浓度而改变其光学和电化学性质。该PFI-TT项目可能会开发协议和制造工艺，以创建便携式传感器并建立PFAS定量检测的性能。易于使用的价格合理的PFAS传感器的可用性和商业化可能会导致更有效，更广泛的可用性和更低的成本分析，这可能会转化为改善环境污染的监测。该奖项反映了NSF的法定使命，并被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。