PFI-TT: Development of Easy-to-Use Affordable Sensors for Rapid Detection of Environmental Pollutants

PFI-TT：开发易于使用且经济实惠的传感器，用于快速检测环境污染物

基本信息

批准号：
2141017
负责人：
Emanuela Andreescu
金额：
$ 25万
依托单位：
Clarkson University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2022
资助国家：
美国
起止时间：
2022-01-01 至 2024-12-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2141017&HistoricalAwards=false
关键词：
PFI TT Development Easy Use

项目摘要

The broader impact/commercial potential of this Partnerships for Innovation - Technology Translation (PFI-TT) project is to create a low cost technology to detect, screen and quantify per- and polyfluoroalkyl substances (PFAS), an emerging group of environmental pollutants. PFAS are used in many commercial products and applications and have recently been identified as posing significant threats to human health. The proposed technology addresses the environmental testing needs for low cost detection of PFAS by providing the tools needed to better estimate their distribution, exposure, and treatment efficacy. Through partnerships with industry and established advanced technology and innovation centers, this PFI-TT project seeks to establish the performance, testing and manufacturing of a portable device for field analysis. Other activities include the development of a go-to-market strategy, customer discovery, and validation. The technology developed in this project may provide broader adoption by non-expert users, providing social and economic benefits in the environmental sector. The team will work with the Shipley Center for Innovation and the Graduate School at Clarkson University to develop new curriculum and workforce development modules covering laboratory management, team science and intellectual property, and teamwork and collaboration in the workplace. The team will also organize workshops to train undergraduate and graduate students in innovation and entrepreneurship. The proposed project seeks to advance the development of programmable receptors that have the capability to react with PFAS through electrostatic and fluoride-specific interactions, generating concentration-dependent changes in the status of the receptors, thus enabling their measurement by low cost spectroscopic and electrochemical techniques. Fundamental investigations of the interaction of PFAS with the receptors have led to the discovery of unique candidates that change their optical and electrochemical properties with the type, length, structure, and concentration of PFAS. This PFI-TT project may develop protocols and a manufacturing processes to create portable sensors and establish performance for quantitative detection of PFAS. The availability and commercialization of easy-to-use affordable PFAS sensors have the potential result in more effective, broadly available, and lower-cost analyses that may translate into improved monitoring of environmental pollution.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这种伙伴关系对创新 - 技术翻译（PFI-TT）项目的更广泛的影响/商业潜力是创建一种低成本技术，以检测，筛查和量化每种环境污染物组（PFAS）（PFAS）。 PFA用于许多商业产品和应用中，最近被确定为对人类健康构成重大威胁。拟议的技术通过提供更好地估计其分布，暴露和治疗功效所需的工具来解决PFA低成本检测的环境测试需求。通过与行业并建立的先进技术和创新中心建立合作伙伴关系，该PFI-TT项目旨在建立便携式设备的性能，测试和制造以进行现场分析。其他活动包括制定进入市场策略，客户发现和验证。该项目开发的技术可能会提供非专业用户的广泛采用，从而在环境部门提供社会和经济利益。该团队将与克拉克森大学的希普利创新中心和研究生院合作，开发新的课程和劳动力发展模块，涵盖了实验室管理，团队科学和知识产权，以及在工作场所的团队合作和协作。该团队还将组织研讨会，以培训创新和企业家精神的本科生和研究生。拟议的项目旨在推动可编程受体的发展，这些受体能够通过静电和氟化物特异性相互作用与PFA反应，从而产生受体状态的浓度依赖性变化，从而通过低成本光谱和电化学技术实现其测量。 PFA与受体相互作用的基本研究导致发现了独特的候选者，这些候选者会随着PFA的类型，长度，结构和浓度改变其光学和电化学性质。这个PFI-TT项目可能会开发协议和制造过程，以创建便携式传感器并建立绩效以定量检测PFA。易于使用的负担得起的PFAS传感器的可用性和商业化具有更有效，可用和低成本的分析的潜在结果，这些分析可能会改善对环境污染的监测。该奖项反映了NSF的法定任务，并被认为是通过基金会的知识分子和广泛影响的评估来评估Criteria的评估。