Gas phase studies of the interactions of electrons with peptide ions: structure assignment and fundamentals

电子与肽离子相互作用的气相研究：结构分配和基础原理

• 批准号: LX0882635
• 负责人: Prof Richard O'Hair
• 金额: $ 5.71万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage - International
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LX0882635
• 关键词: Gas; phase; studies; interactions; electrons

Electron-induced reactions are fundamental to a wide range of processes that underlie many areas of science and technology, ranging from planetary atmospheres, industrial plasmas to living tissues. Since ionizing radiation is believed to be a major cause of damage to living cells, understanding electron interactions with biological molecules is essential to predict the consequences of exposure. Structure determination of biomolecules is at the heart of identifying, diagnosing and potentially developing treatments for diseases, and thus another important reason for studying these interactions is the potential to develop new mass spectrometry based analytical methods.

电子诱导反应是许多科学和技术领域的基础，从行星大气层，工业等离子体到活组织的广泛过程的基础。由于电离辐射被认为是活细胞损伤的主要原因，因此了解电子与生物分子的相互作用对于预测暴露的后果至关重要。生物分子的结构测定是识别，诊断和潜在开发疾病治疗的核心，因此研究这些相互作用的另一个重要原因是开发新的基于质谱的分析方法的潜力。