Elucidating the Dynamics of Memory

阐明记忆的动态

• 批准号: 19H01012
• 负责人: McHugh Thomas
• 金额: $ 21.47万
• 依托单位: Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19H01012/
• 关键词: hippocampus; memory; cortex; engram; physiology; Memory; ripples; consolidation

This grant was only active for 3 months due to the awarding of a KIBAN S on the same research topic in 07/2019. During that period I actively prepared for experiments examining the physiology of cFos positive neurons in regions upstream and downstream of CA1, CA3 and the mPFC (ACC). We bred the necessary mice for the experiments and prepared the required viral and physiological reagents. Pilot injects were conducted to control the timeline of viral expression and ensure both regions can be targeted.

由于在07/2019中就同一研究主题授予了KIBAN S，因此该补助金仅有效3个月。在此期间，我积极准备实验，检查CA 1，CA 3和mPFC（ACC）上游和下游区域cFos阳性神经元的生理学。我们培育了实验所需的小鼠，并准备了所需的病毒和生理试剂。进行中试注射以控制病毒表达的时间轴并确保两个区域都可以被靶向。