Developmental Research for Computer Diagnostic System of Disorders of Motor Function by Using the 2-Dimensional Manual Control System

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Recently, medical treatment for intractable diseases attended with disorders of the motor function such as Parkinson syndrome, cerebellar ataxia, muscular dystrophy, apoplexy, and so on has become of general interest. In order to diagnose these diseases efficiently in an early stage, a new method of examining the human motor function should be developed. The major purpose of our researches is to develop a new examination system of the motor function using the 2-dimensional manual control system so that we can quantitatively evaluate medical therapy or rehabilitation and make an automatic diagnosis by using a personal computer system.First, several experiments in the 1-dimensional manual control system have shown the effects of two central nervous system diseases, i.e. Parkinsonism and cerebellar ataxia, on the predictive control function of voluntary movements. This has indicated that the learning process, the power spectrum of rate of the manipulated variable and the coherency functio … More n can become useful parameters to make a diagnosis for discriminating the diseases.Moreover, we have studied human adaptability to the reference input in the manual control system and shown that the proposed model realizing output regulation for a linear system with delay can approximate the frequency response which cannot be explained easily by usual models.Using the experiments in the 2-dimensional manual control system in which either the horizontal polarity or the vertical one of the controlled object is reversed, we have shown that the control characteristics of the human operator have anisotropy with respect to the reverse direction of the controlled object.The system proposed in this study can make an objective and quantitative examination of the integration function of visual and somatic sensations which cannot be carried out by any other neurological tests and could give a more practical and effective examination method by introducing some computer algorithms for an automatic diagnosis. Less