Developmental Research for Computer Diagnostic System of Disorders of Motor Function by Using the 2-Dimensional Manual Control System

二维手动控制系统运动功能障碍计算机诊断系统的开发研究

基本信息

  • 批准号:
    59890003
  • 负责人:
  • 金额:
    $ 2.62万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Developmental Scientific Research
  • 财政年份:
    1984
  • 资助国家:
    日本
  • 起止时间:
    1984 至 1985
  • 项目状态:
    已结题

项目摘要

Recently, medical treatment for intractable diseases attended with disorders of the motor function such as Parkinson syndrome, cerebellar ataxia, muscular dystrophy, apoplexy, and so on has become of general interest. In order to diagnose these diseases efficiently in an early stage, a new method of examining the human motor function should be developed. The major purpose of our researches is to develop a new examination system of the motor function using the 2-dimensional manual control system so that we can quantitatively evaluate medical therapy or rehabilitation and make an automatic diagnosis by using a personal computer system.First, several experiments in the 1-dimensional manual control system have shown the effects of two central nervous system diseases, i.e. Parkinsonism and cerebellar ataxia, on the predictive control function of voluntary movements. This has indicated that the learning process, the power spectrum of rate of the manipulated variable and the coherency functio … More n can become useful parameters to make a diagnosis for discriminating the diseases.Moreover, we have studied human adaptability to the reference input in the manual control system and shown that the proposed model realizing output regulation for a linear system with delay can approximate the frequency response which cannot be explained easily by usual models.Using the experiments in the 2-dimensional manual control system in which either the horizontal polarity or the vertical one of the controlled object is reversed, we have shown that the control characteristics of the human operator have anisotropy with respect to the reverse direction of the controlled object.The system proposed in this study can make an objective and quantitative examination of the integration function of visual and somatic sensations which cannot be carried out by any other neurological tests and could give a more practical and effective examination method by introducing some computer algorithms for an automatic diagnosis. Less
近年来,帕金森综合征、小脑性共济失调、肌营养不良、中风等伴有运动功能障碍的顽固性疾病的医学治疗已成为人们普遍关注的问题。为了在早期有效地诊断这些疾病,需要开发一种新的检测人体运动功能的方法。本研究的主要目的是利用二维手动控制系统开发一种新的运动功能检测系统,以便利用个人计算机系统对医学治疗或康复进行定量评估和自动诊断。首先,在一维手动控制系统中的几个实验表明,帕金森病和小脑性共济失调这两种中枢神经系统疾病对随意运动的预测控制功能的影响。这表明,学习过程、被操纵变量的速率功率谱和…的一致性函数本文还研究了人工控制系统中人类对参考输入的适应性,证明了所提出的实现线性时滞系统输出调节的模型能够逼近通常模型难以解释的频率响应。在被控对象水平或垂直极性反转的二维人工控制系统中进行的实验表明,研究表明,操作者的控制特性相对于被控对象的反向具有各向异性,本研究提出的系统可以对视觉和躯体感觉的整合功能进行客观、定量的检测,这是任何其他神经学测试都无法完成的,通过引入一些计算机算法进行自动诊断,可以给出一种更实用、更有效的检测方法。较少

项目成果

期刊论文数量(6)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Medical Electronics and Biological Engineering, Japan. 23-3. (1985)
医学电子和生物工程,日本。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Human Posture, Japan. 5-1. (1985)
人体姿势,日本。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
姿勢研究. 5-1. (1985)
姿势研究。5-1。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
IEEE Trans.on System,Man & Cyber.Submitted. (1986)
IEEE Trans.on 系统,人与网络。已提交 (1986)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
医用電子と生体工学. 23-3. (1985)
医疗电子和生物工程23-3。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
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TAKEDA Hiroshi其他文献

TAKEDA Hiroshi的其他文献

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{{ truncateString('TAKEDA Hiroshi', 18)}}的其他基金

Research on interrelationship between management philosophy, investment behavior, and financial policy in amoeba management
阿米巴经营中管理理念、投资行为与财务政策的相互关系研究
  • 批准号:
    19K01866
  • 财政年份:
    2019
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Research on amoeba management from corporate finance perspective
公司财务视角下的阿米巴经营研究
  • 批准号:
    15K03610
  • 财政年份:
    2015
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Rikkunshito increased hypothalamic SIRT1 activity
Rikkunshito 增加下丘脑 SIRT1 活性
  • 批准号:
    25460922
  • 财政年份:
    2013
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Relationship between the gloval solvability and a non-lineaer action for a nonlinear damped wave equation
非线性阻尼波动方程的全局可解性与非线性作用之间的关系
  • 批准号:
    23740116
  • 财政年份:
    2011
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Elucidation of the epigenetic regulation on the stress resistance
阐明抗逆性的表观遗传调控
  • 批准号:
    22590086
  • 财政年份:
    2010
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The mechanism by which rikkunshito increases acylated ghrelin
rikkunshito 增加酰化 ghrelin 的机制
  • 批准号:
    22590676
  • 财政年份:
    2010
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Dynamics and maintenance of soil animal communities depending upon the fine root production in tropical seasonal forests
土壤动物群落的动态和维持取决于热带季节性森林细根的生产
  • 批准号:
    17405029
  • 财政年份:
    2005
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Comparative Study about Effectiveness of the Care Systems : Japan, Sweden UK and Germany
日本、瑞典、英国和德国护理系统有效性的比较研究
  • 批准号:
    10041089
  • 财政年份:
    1998
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A).
Comparative Study on the Administration and Finance of the Care Security Systems: Japan and European Counties
日本与欧洲国家护理保障制度管理与财务的比较研究
  • 批准号:
    10490028
  • 财政年份:
    1998
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Helicobacter pylori and its association with gastric cancer
幽门螺杆菌及其与胃癌的关系
  • 批准号:
    09670502
  • 财政年份:
    1997
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

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Tiny RNAs as new potential biomarkers for gammaherpesvirus-driven neurological and central nervous system diseases
微小RNA作为伽马疱疹病毒驱动的神经和中枢神经系统疾病的新潜在生物标志物
  • 批准号:
    10727761
  • 财政年份:
    2023
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    $ 2.62万
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Acquisition mechanism of brain-specific properties for regulatory T cells in central nervous system diseases
中枢神经系统疾病中调节性T细胞脑特异性特性的获取机制
  • 批准号:
    21K06951
  • 财政年份:
    2021
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Creation of blood-brain barrier transparent artificial nanoparticles for the treatment of central nervous system diseases
血脑屏障透明人工纳米粒子的研制用于治疗中枢神经系统疾病
  • 批准号:
    20J20737
  • 财政年份:
    2020
  • 资助金额:
    $ 2.62万
  • 项目类别:
    Grant-in-Aid for JSPS Fellows
Drug development of central nervous system diseases using dynamic three-dimensional in vitro blood-brain barrier model
利用动态三维体外血脑屏障模型进行中枢神经系统疾病药物开发
  • 批准号:
    20KK0254
  • 财政年份:
    2020
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    Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
Targeting Blood-Brain Barrier Protection to Develop Therapeutic Agents for Central Nervous System Diseases
以血脑屏障保护为目标开发中枢神经系统疾病的治疗药物
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    18K08973
  • 财政年份:
    2018
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    Grant-in-Aid for Scientific Research (C)
Development of self-assembled polymeric vehicles selectively delivering drugs to specific brain cells toward treatment of central nervous system diseases
开发自组装聚合物载体选择性地将药物递送至特定脑细胞以治疗中枢神经系统疾病
  • 批准号:
    17H04742
  • 财政年份:
    2017
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    $ 2.62万
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    Grant-in-Aid for Young Scientists (A)
"Brain-type" glycosylation: A tag for diagnostic markers of central nervous system diseases
“脑型”糖基化:中枢神经系统疾病诊断标记物的标签
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    26460394
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    2014
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    Grant-in-Aid for Scientific Research (C)
Search for biomarkers of central nervous system diseases that show subtle morphological changes on MRI and CT.
寻找在 MRI 和 CT 上显示出细微形态变化的中枢神经系统疾病生物标志物。
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    23590367
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    2011
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    $ 2.62万
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Development and clinical application of cardiac-gated cerebrospinal space MR imaging for central nervous system diseases
心门控脑脊间隙磁共振成像治疗中枢神经系统疾病的进展及临床应用
  • 批准号:
    21791189
  • 财政年份:
    2009
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The role of chemoattractant receptors in central nervous system diseases
趋化受体在中枢神经系统疾病中的作用
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    8274293
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    2008
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    $ 2.62万
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