A sustainable cellular factory for the production of antibiotics by photosynthetic bacteria
A sustainable cellular factory for the production of antibiotics by photosynthetic bacteria
批准号:
LP0668313
负责人:
Prof Brett Neilan
金额:
$15.3万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2006
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2006-05-30 至 2009-12-31
中文摘要
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英文摘要
The range and rate of natural product discovery is the limiting factor in developing new pharmaceuticals. Traditional methods for the screening of these compounds or for their chemical synthesis are rapidly becoming inadequate as an increasing number of specific therapies, for cancers and infectious diseases for instance, are required. The research proposed will enable the design and production of "unnatural" products, including novel antibiotics, via combinatorial biosynthesis in photosynthetic microorgansims. The outcomes include graduate student training and Australian innovation in an enormous global market that is awaiting the next generation of medicines and associated pharmaceutical production technologies.
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