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Histo-pathological Studies on the Effects of the Natural Coral Powdered as Pulp Capping Materials after Vital Dental Pulp Amputation

天然珊瑚粉作为盖髓材料对活体牙髓截除术后效果的组织病理学研究

基本信息

批准号：
04671176
负责人：
INOUE Hiroshi
金额：
$ 1.34万
依托单位：
Fukuoka Dental College
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1993
项目状态：
已结题

项目摘要

As natural powdered corals appear to be effective as dental pulp capping materials, they were analyzed with x-ray detection energy dispersive analysis (Kevex 7000 Q) and with x-ray diffraction (experiment 1). The effects of the natural powdered coral for use as dental pulp capping material, on the surrounding tissues implanted (experiment 2) and on the dog dental pulp amputated (experiment 3) were elucidated histo-pathologically and ultrastructurally at various intervals after treatment. For experiment 2, two types of natural corals powdered namely, white and porous, A, and red and dense, B, and the two heated at 700ﾟC for 30 min, which were previously kept in the polyethylene tubes (3.0X7.0mm), were implanted subcutaneously into the dorsal tissues of 36 rats for 2 to 6 months. For experiment 3, natural powdered coral A and A heated were placed on the dog dental pulp of 64 teeth, coronal pulp of which was previously amputated with round bars(#5) and exscavators sterilized, and treated … More routinely for 1 to 7 weeks after treatment. As a control, calcium hydroxide was placed on the dental pulp of 12 dog teeth instead of the natural powdered coral for the same intervals. At various intervals after treatment for both experiments, the surrounding tissue was carefully removed, fixed, embedded in paraffin or Epon 812 and sectioned routinely for light- and scanning or transmission electron-microscopy.The degree of the inflammatory reaction in the surrounding connective tissues to 4 types of corals implanted subcutaneously was slightly different each other. In particular, the tissues adjacent to natural coral A were more strongly encapsulated with the dense fibrous tissues than those adjacent to the other coral at all intervals after treatment. However, in tissues adjacent to the concaved surfaces of all types of coral implanted, the inflammatory response remained at all intervals. The dent in bridge was not positivelyformed over the dental pulp amputated at 1 to 3 weeks after natural or heated coral A treatment, whereas at 5 to 7 weeks the bonelike dentin bridge was observed on 50% of theexperimental teeth treated with natural coral A, but not with heated coral A.The necro-sis of the dental pulp adjacent to natural and heated coral A were not observed over theexperimental periods. In the heated coral A and B, and natural coral A and B, Ca, P, Mg, Fe and Al ions were observed but the ratio of Mg and Al was different in the A and B types of corals.Natural coral A showed a characteristic peak as observed with calcite. Less

由于天然珊瑚粉是一种有效的牙髓盖髓材料，对它们进行了X射线检测能量色散分析(Kevin Ex 7000Q)和X射线衍射分析(实验1)。本文从组织病理学和超微结构的角度研究了天然珊瑚粉作为牙髓盖髓材料、对周围组织的影响(实验2)和对犬牙髓切除的影响(实验3)。在实验2中，将预先放置在聚乙烯管(3.0×7.0 mm)中的白色多孔A和红色致密B两种天然珊瑚粉末以及在700ﾟC加热30min的两种天然珊瑚粉末植入36只大鼠背部组织2~6个月。在实验3中，将天然珊瑚A粉和加热的珊瑚A粉分别放置在牙的牙髓上，用圆棒(#5)截断其冠髓，并用翻盖器消毒，处理…更常规的是在治疗后1-7周。作为对照，在12颗狗牙齿的牙髓上放置氢氧化钙，而不是在相同间隔内放置天然珊瑚粉。两种实验均在治疗后不同的时间间隔，仔细取出周围组织，固定，包埋石蜡或EPON 812，常规切片，进行光镜、扫描或透射电子显微镜观察。4种珊瑚皮下植入后，周围结缔组织的炎症反应程度略有不同。特别是，天然珊瑚A附近的组织在治疗后的所有时间段都比其他珊瑚附近的组织被致密的纤维组织包裹得更紧密。然而，在植入的所有类型的珊瑚凹面附近的组织中，炎症反应保持在所有时间间隔。在天然珊瑚A和加热珊瑚A处理后1~3周，切断的牙髓上未见桥状凹陷，而在5~7周时，天然珊瑚A处理的实验牙中有50%观察到骨样牙本质桥，而加热珊瑚A处理的牙髓未见明显的骨性凹陷。在受热珊瑚A、B和天然珊瑚A、B中，观察到钙、磷、镁、铁、铝离子，但在A、B类珊瑚中，镁、铝的比例不同，天然珊瑚A与方解石的特征峰相同。较少