Neuro-theoretical analysis of brain rhythmic information in cognitive and verbal behavior

本研究对人类认知/语言过程与大脑节律信息的关系进行了研究，并得到以下结果：1.基于神经突触回路分析认知/语言相关节律活动的产生，我们将感觉区-丘脑和丘脑-隔区的神经突触回路作为双向的皮层-皮层下系统进行建模和仿真。针对脑电/脑磁图中的节律信息，提出了一种基于模板的2D样条插值和自适应相关滤波的单次节律脉冲串提取算法，并将其应用于3D脑图像中。3.为了建立一种认知/言语行为脑节律信息的检测方法，4etc.in.为了研究认知/言语节律信息与神经递质/调节剂代谢产物之间的关系，我们分析了认知/言语任务中的血浆代谢物以及大脑节律活动，以研究所构建的模型。语言障碍，我们开发了电路模型，提出了一个模型的神经信息处理解释缺陷之间的关系，在认知/言语行为，在神经递质/调制代谢和脑电图/MEG以及眼球运动。

We investigated and got following results on the relationship between human cognitive/verbal process and brain rhythmic information.1.For analyzing generation of cognition-/language-related rhythmic activities based on neurosynaptic circuits, we modeled and simulated neurosynaptic circuits of sensory area-thalamus and hippocampus-septum as bi-directional cortico-subcortical system.2.For developing a method of time series analysis of single-trial rhythmic information from EEG/MEG,we modified and integrated 2D-spline interpolation and adaptive correlation filter with templates to complete an algorithm of extracting a single-trial rhythmic bursts as well as of estimating source localization to be presented in 3D brain image.3.For establishing a testing method of brain rhythmic information in cognitive/verbal behavior, we analyzed characteristics of rhythmic structure with fractals etc.in the cognitive and verbal data acquired by EEG/MEG system as well as eyetracker.4.For invetigating relationships between cognitive/verbal rhythmic information and neurotransmitter/modulator metabolites, we analyzed plasma metabolites as well as brain rhythmic activities during cognitive/verbal tasks to investigate the constructed model.5.For modeling of rhythmic activities in cognitive/verbal disorders, we developed the circuit model to propose a model of neural information processing explaining the relations among deficits in cognitive/verbal behavior, in neurotransmitter/modulator metabolites and in EEG/MEG as well as eye movements.