权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Development on evaluation method of thought and personality disorders based on quantitative individuality of language behavior and brain functional information

基于语言行为个性化和脑功能信息的思维与人格障碍评估方法研究进展

基本信息

批准号：
11680836
负责人：
ITOH Kenji
金额：
$ 2.18万
依托单位：
University of Tokyo
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2000
项目状态：
已结题

项目摘要

We investigated and got following results on the development of objective evaluation method for thought and personality disorders as well as for treatments including SST(social skill training)based on four types of personality-related data, i.e., brain activity data, results from mental test, behavioral pattern in dialogue, cognitive impression on mental states emerged from subjects.extraction method of individuality in spoken language and thought process.1. We analyzed brain metabolic data from blood metabolities of neuromodulators as candidates of individuality.2. We extracted individuality in multi-channel EEG and MEG topographies which are related to linguistic and thought process.3. We measured diagnostic behaviors of thought and personality disordered patients in treatments.4. We found individuality and abnormality in MR images of cortico-subcortical system.5. We improved mental and psychological tests to be a computer-controlled testing system with simultaneous measuring of brain functional images.6. We developed a method for extracting individualities from multi-channel EEG and MEG data as well as from speech and body expression.7. We presented a model on individuality on the basis of contributions of neurotransmitters and modulators projected to cerebro-celebellar system.8. We applied cross-correlation analysis on speech and body movements to quantify diagnostic characteristics and disordered patterns.9. We constructed a integrated database of brain functional and behavioral data in tests and treatments to apply subjective and quantified evaluation of thought and personality disorders.

我们调查并获得了以下结果，即基于四种类型的人格相关数据，大脑活动数据、心理测试结果、对话中的行为模式、被试对心理状态的认知印象、口语和思维过程中个性的提取方法.我们分析了脑代谢数据从血液代谢的神经调质作为个体的候选人.在多通道脑电和脑磁图中提取与语言和思维过程相关的个体特征.测量治疗中思维障碍和人格障碍患者的诊断行为.皮质-皮质下系统MRI表现有个体性和异常性.我们将心理测验改进为计算机控制的同时测量脑功能图像的测验系统.我们开发了一种从多通道EEG和MEG数据以及从语音和身体表达中提取个性的方法。我们提出了一个模型的基础上的贡献的神经递质和调制器投射到大脑-小脑系统的个性。我们应用语言和身体动作的互相关分析来量化诊断特征和紊乱模式。我们构建了一个整合的测试和治疗中的脑功能和行为数据的数据库，用于对思维和人格障碍进行主观和量化的评估。