Development of New Degradation Methods of Strongly Persistent organic Pollutants like Perfluorocompounds in Water and Sludge Treatment System

全氟辛烷磺酸（PFOS）和全氟辛酸（PFOA）等全氟化合物（PFCs）的持久性和毒性，引起了人们的严重关注。作为这项调查的第一步，LC/MS/MS方法，同时定量不同类型的PFCs与适当的水和固体样品的预处理开发。低压反渗透膜对PFOS和PFOA的分离效果较好。此外，全氟辛酸通过组合波长（即185 nm+254 nm）的紫外光分解可有效降解。此外，使用铂电极的电解法可非常有效地降解全氟辛酸和全氟辛烷磺酸。在600 oC以上的温度下，间接热脱附技术可以有效去除固相中的PFOS和PFOA。CHO细胞MN试验和HepG 2细胞MTT试验结果表明，PFOS对细胞具有毒性，导致脂质代谢紊乱。

Detection of perfluorocompounds (PFCs) such as PFOS (perfluorooctane sulfonate) and PFOA (perfluorooctanoic acid) particularly in water environment has raised serious concerns among people due to persistent and toxic characteristics of the compounds. As the first step in this investigation, a LC/MS/MS method for simultaneous quantification of different types of PFCs with appropriate pretreatments for water and solid samples was developed. PFOS and PFOA were almost separated by Low Pressure Reverse Osmosis Membrane. In addition, PFOA was effectively degraded by UV photolysis with combined wavelengths (i.e. 185 nm+254 nm). Moreover, both PFOA and PFOS were very effectively degraded with electrolytic methods using platinum electrodes. Several PFCs including PFOS and PFOA in solid phase were effectively eliminated by indirect thermal desorption technique with temperature more than 600 oC. Test results on MN assay with CHO cells and MTT assay with HepG2 cells suggested PFOS toxicity to the cells resulting in lipid metabolism disorder.