Nuclear receptor-mediated bisphenol endocrine disrupting signal toxicity
Nuclear receptor-mediated bisphenol endocrine disrupting signal toxicity
批准号:
15H01741
负责人:
SHIMOHIGASHI Yasuyuki
金额:
$29.54万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2018-03-31
中文摘要
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英文摘要
期刊论文(78)
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ペプチド科学研究に寄与する非ペプチド研究
非肽研究有助于肽科学研究
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Arai Y, Hayakawa K, Arai D, Ito R, Iwasaki Y, Saito K, Akutsu K, Takatori S, Ishii R, Hayashi R, Izumi S, Sugino N, Kondo F, Horie M, Nakazawa H, Makino T, Hirosawa M, Shiota K, Ohgane J., 下東康幸]
通讯作者:
下東康幸
エストロゲン関係受容体の協働作用によりビスフェノールAの低用量効果が生まれる分子メカニズム(The molecular mechanism of a low-dose effect of bisphenols by the synergetic interaction of estrogen-related receptors)
雌激素相关受体协同作用双酚低剂量作用的分子机制
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Kikuchi, Y., Kanematsu, Y., Yoshikawa, N., Okubo, T., Takagaki, M., 劉 暁輝・池田 伸・松島綾美・下東康幸]
通讯作者:
劉 暁輝・池田 伸・松島綾美・下東康幸
核内受容体ERおよびERRの協働作用による転写活性増強の分子メカニズム (Molecular mechanism of transcription activity enhancement in the synergetic interaction between the nuclear receptors ER and ERR)
核受体ER和ERR协同相互作用增强转录活性的分子机制
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[桂真理, 戸澤英人, 南斎ひろ子, 小野久子, 小林美佳, 田口明糸, 石川夕記子, 興梠貴英, 曽根秀子, 和田洋一郎, 劉 暁輝・池田 伸・松島綾美・下東康幸]
通讯作者:
劉 暁輝・池田 伸・松島綾美・下東康幸
エストロゲン受容体の受容体活性化におけるホモダイマー化の構造要因 (Estrogen receptor structural essentials in the homodimerization necessary for receptor activation)
受体激活所需的同二聚化中雌激素受体的结构要点
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[青木輝夫, 庭野匡思, 谷川朋範, 石元裕史, 堀雅裕, 島田利元, 的場澄人, 山崎哲秀, 山口悟, 藤田耕史, 本山秀明, 藤渕航, 兼松祐一郎・大久保達也・菊池康紀, 﨑戸沙耶・藤山明菜・劉 暁輝・松島綾美・下東康幸]
通讯作者:
﨑戸沙耶・藤山明菜・劉 暁輝・松島綾美・下東康幸
Mutual co-work between nuclear receptor ERα and ERRγ requires their homodimerization
核受体 ERα 和 ERRγ 之间的相互协作需要它们同源二聚化
DOI:
--
发表时间:
2018
期刊:
Peptide Science 2017
影响因子:
--
作者:
[X. Liu, M. Shimohigashi, M. Sugiyama, A. Matsushima, and Y. Shimohigashi]
通讯作者:
and Y. Shimohigashi
共 68 条
Invention of superagonists and superantagonists for ORL1 nociceptin receptor
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批准号:23657078
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2011
-
负责人:SHIMOHIGASHI Yasuyuki
-
依托单位:
Signal toxicity mediated through nuclear receptors of new generation bisphenols
-
批准号:22221005
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$100.34万
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财政年份:2010
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负责人:SHIMOHIGASHI Yasuyuki
-
依托单位:
Elucidation of bisphenol A low-dose effects mediated through the nuclear receptor ERRγ
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批准号:19201012
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.37万
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财政年份:2007
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负责人:SHIMOHIGASHI Yasuyuki
-
依托单位:
Risk assessment of endocrine disruptors in nuclear receptors by means of antibody-sensing method to measure the conformation change associated with ligand binding
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批准号:16310044
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.92万
-
财政年份:2004
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负责人:SHIMOHIGASHI Yasuyuki
-
依托单位:
Novel Bioactive Conformation Constructed by Structurally Constrained CH/π Interaction between Amino Acids Side Chains
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批准号:10480152
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.68万
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财政年份:1998
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负责人:SHIMOHIGASHI Yasuyuki
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依托单位:
Joint Study on Molecular Mechanism of Opioid Receptors
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批准号:09044230
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$4.48万
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财政年份:1997
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负责人:SHIMOHIGASHI Yasuyuki
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依托单位:
Studies on the molecular mechanism of thrombin receptor activation by means of ligand peptides containing a series of fluorinated phenylalanines
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批准号:08458178
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.03万
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财政年份:1996
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负责人:SHIMOHIGASHI Yasuyuki
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依托单位:
海外基金