Development of New Catalytic Reactions Directed to Straightforward Synthesis of Unused Carbon Sources

镍配合物在苯甲醚衍生物的铃木偶联、胺化和还原反应中表现出较高的催化活性，这涉及到碳-甲氧基键的活化。发现硅铑是活化C-CN键的优良催化活性物质。我们发现硅基化、硼基化和苯基化反应涉及C-CN键的裂解。基于这些结果，我们成功地发现了一种新的合成苯并硅酮的方法，它具有有趣的电子性质。我们在含有8-氨基喹啉导向基团的脂肪酰胺中发现了钌催化的C(sp3)-H键羰基化。

It was found that nickel complexes show high catalytic activity in Suzuki coupling, amination and reduction of anisole derivatives, which involve the activation of carbon-methoxy bonds. Silyl-rhodium species were found to be a superior catalytic active species for the activation of C-CN bonds. We found silylation, borylation, and phenylation reactions involving the cleavage of C-CN bonds. Based on these results, we successfully discovered a new synthesis of benzosiloles, which have interesting electronic properties. We found the Ru-catalyzed carbonylation of C(sp3)-H bonds in aliphatic amides that contain an 8-aminoquinoline directing group.