Development of monitoring system for effects of ultra low level microwave with changing
Development of monitoring system for effects of ultra low level microwave with changing
批准号:
12557035
负责人:
NAKAMURA Hiroyuki
金额:
$8.13万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2001
中文摘要
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英文摘要
We developed microwave device simulating actual environmental exposure of very low level with changing frequencies produced by recent communicating instruments. The field was generated by signal simulation of the Global System for Mobile communications (GSM) of 960 MHz. Subjects were exposed in a specially constructed chamber, a Transverse Electromagnetic (TEM) cell. The Specific Absorption Rate (SAR) value for each cell well was calculated for this exposure system. Microwaves of 2 and 10 mW/cm^2 elevated 0.98±0.12, 3.70±0.15℃ (Mean±SE) , respectively, of rectal temperature hi rats after continuous exposure of 90 min, and 0.22±0.19, 1.69±0.20℃, respectively after 180 min. Heat during microwaves produce uteroplacental circulatory disturbances, "subsequently causing abortion. The decreases in uteroplacental blood flow accompanying microwaves of 2 and 10 mW/cm^2 were reversible and irreversible changes, respectively. Pretreatment with progesterone receptor antagonist mifepristone produced irreversible change during microwaves of 2 mW/cm^2 with a simultaneous decrease in Prostaglandin (PG)E_2, but not changed NK cell activity. Therefore, the irreversible decrease in uteroplacental blood flow seems to be due to the actions of progesterone and PGE_2.in cooperation with cellular immune function. The homeostasis of endocrine-immune system is important to prevent pregnancy from effects of ultra low level microwaves with changing frequencies.
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Nakamura H,Nagase H,Ogino K,Hatta K and Matuzaki I: "Uteroplacental circulatory disturbance in pregnant rats exposed to microwaves through actions of prostaglandin F2α"Reprod Toxicol. 14. 235-240 (2000)
Nakamura H、Nagase H、Ogino K、Hatta K 和 Matuzaki I:“通过前列腺素 F2α 的作用,暴露于微波的怀孕大鼠的子宫胎盘循环障碍”Reprod Toxicol. 14. 235-240 (2000)
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Nakamura H, Ogawa Y, Nagase H, Nakajima M, Kodama N, Ogino K, Ooshita Y: "Natural killer cell activity and its related psychological factor, sense of coherence in male smokers"J Occup Health. 43. 191-8 (2001)
Nakamura H、Okawa Y、Nagase H、Nakajima M、Kodama N、Ogino K、Ooshita Y:“男性吸烟者的自然杀伤细胞活性及其相关心理因素、连贯感”J Occup Health。
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Nakamura H,Nagase H,Ogino K,Hatta K and Matuzaki I: "Heat produces uteroplacental circulatory disturbance in pregnant rats through action of corticotropin releasing hormone (CRH)"Placenta. 21. 510-515 (2000)
Nakamura H、Nagase H、Ogino K、Hatta K 和 Matuzaki I:“热量通过促肾上腺皮质激素释放激素 (CRH) 的作用在怀孕大鼠中产生子宫胎盘循环障碍”胎盘。
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Nakamura H, Nagase H, Ogino K, Hatta K, Matsuzaki I: "Heat produces uteroplacental circulatory disturbance in pregnant rats through action of corticotropin releasing hormone (CRH)"Placenta. 21. 510-5 (2000)
Nakamura H、Nagase H、Ogino K、Hatta K、Matsuzaki I:“热量通过促肾上腺皮质激素释放激素 (CRH) 的作用在怀孕大鼠中产生子宫胎盘循环障碍”胎盘。
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Nakamura H, Nagase H, Ogino K, Hatta K, Matsuzaki I: "Involvement of central, but not placental corticotropin releasing hormone(CRH) in heat stress-induced immunosuooression during pregnancy"Brain Behav Immun. 15. 43-53 (2001)
Nakamura H、Nagase H、Ogino K、Hatta K、Matsuzaki I:“中枢但不是胎盘促肾上腺皮质激素释放激素 (CRH) 参与妊娠期间热应激诱导的免疫抑制”脑行为免疫。
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