A functional MRI study on the regulation of stress mediated brain activity by biting.

一项功能性核磁共振研究，研究咬合对压力介导的大脑活动的调节。

• 批准号: 22592063
• 负责人: NAKAMURA Hiroyuki
• 金额: $ 2.83万
• 依托单位: Gifu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22592063/
• 关键词: 口腔生理学; 脳活動; 運動野; 下頭頂小葉; 扁桃体; fMRI; 噛み締め; ストレス; 脳; 神経; 非侵襲的画像計測

The aim of this study is to identify if the emotional brain activity is modified by biting. We analyzed activation of several brain regions ob human subjects by using functional magnetic resonance imaging (fMRI) under different biting pressure. The biting pressure was monitored using a flat pressure sensor attached to clear retainer and was visually feed-backed to the subjects. Biting activated the occipito-temporal visual areas, the parietal visual association areas, the primary and secondary somatosensory areas, and the primary motor area. We found that the neuronal activity of amygdala was suppressed by biting.

这项研究的目的是确定情绪的大脑活动是否会因咬而改变。我们用功能磁共振成像（fMRI）分析了人类受试者在不同咬合压力下几个脑区的激活。使用连接到透明保持器的扁平压力传感器监测咬合压力，并视觉反馈给受试者。咬合激活了枕颞视觉区、顶叶视觉联合区、初级和次级躯体感觉区以及初级运动区。我们发现，杏仁核的神经元活动受到抑制咬。

项目成果

Neuroanatomy Research Advances

神经解剖学研究进展

• 发表时间: 2010
• 作者: Nakamura H;Itoh K.(Flynn CE;Callagphan BR)
• 通讯作者: Callagphan BR)

The locus coeruleus projects to the mesencephalic trigeminal nucleus in rats.

大鼠的蓝斑投射到中脑三叉神经核。

• 发表时间: 2010
• 期刊: Neuroscience Research 68
• 作者: Takahashi;T.;Shirasu;M.;Shirasu;M.;Kubo;K.;Onozuka;M.;Sato;S.;Itoh;K.;Nakamura;H.
• 通讯作者: H.

Forming a negative impression of another person correlates with activation in medial prefrontal cortex and amygdala

对另一个人形成负面印象与内侧前额叶皮层和杏仁核的激活相关

• 发表时间: 2011
• 期刊: Soc Cogn Affect Neurosci
• 作者: Iidaka T;et al
• 通讯作者: et al

Direct projections from the central amygdaloid nucleus to the mesencephalic trigeminal nucleus in rats

• DOI: 10.1016/j.brainres.2011.05.026
• 发表时间: 2011-07
• 期刊: Brain Research
• 影响因子: 2.9
• 作者: M. Shirasu;Takeshi Takahashi;Toshiharu Yamamoto;K. Itoh;S. Sato;Hiroyuki Nakamura