Study on a regulation system of intracellular cholesterol transport by ceramide kinase
Study on a regulation system of intracellular cholesterol transport by ceramide kinase
批准号:
24790066
负责人:
NAKAMURA Hiroyuki
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Ceramide kinase produces the bioactive lipid ceramide-1-phosphate and appears as a key enzyme for regulating cell growth and arachidonic acid metabolism. In this study, to elucidate a novel physiological function, we focused on the transport of intracellular cholesterol. We showed that ceramide kinase is a negative regulator of the cholesterol transport from late endosomes to endoplasmic reticulum.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
スフィンゴ脂質によるマスト細胞脱顆粒反応調節機構の解明,次世代を担う創薬
阐明鞘脂对肥大细胞脱颗粒反应的调节机制,下一代药物发现
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Toyomura K, Saito T, Emori S, Matsumoto I, Kato E, Kaneko M, Okuma Y, Nakamura H, Murayama T, 中村浩之,森山友太,牧山智彦,江森俊介,山下尚大,山崎璃沙,村山俊彦, 山崎璃沙,松澤康雄,川島辰男,柳原まどか,中村浩之,藤野裕道,村山俊彦, 鰐川雅裕,中村浩之,藤野裕道,村山俊彦, 牧山智彦,中村浩之,村山俊彦]
通讯作者:
牧山智彦,中村浩之,村山俊彦
TGF-β1による肺線維化への免疫抑制剤への影響
免疫抑制剂对TGF-β1诱导的肺纤维化的影响
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Toyomura K, Saito T, Emori S, Matsumoto I, Kato E, Kaneko M, Okuma Y, Nakamura H, Murayama T, 中村浩之,森山友太,牧山智彦,江森俊介,山下尚大,山崎璃沙,村山俊彦, 山崎璃沙,松澤康雄,川島辰男,柳原まどか,中村浩之,藤野裕道,村山俊彦, 鰐川雅裕,中村浩之,藤野裕道,村山俊彦, 牧山智彦,中村浩之,村山俊彦, 山崎璃沙,松澤康雄,川島辰男,柳原まどか,中村浩之,藤野裕道,村山俊彦]
通讯作者:
山崎璃沙,松澤康雄,川島辰男,柳原まどか,中村浩之,藤野裕道,村山俊彦
Arachidonic acid metabolism via cytosolic phospholipase A2alpha induces cytotoxicity in niemann-pick disease type C cells.
花生四烯酸通过胞质磷脂酶 A2α 代谢可诱导尼曼皮克病 C 型细胞的细胞毒性。
DOI:
10.1002/jcp.23025
发表时间:
2012
期刊:
J Cell Physiol
影响因子:
5.6
作者:
[山口 賀章, 岡村 均, 松下 英明, Nakamura H. et al.]
通讯作者:
Nakamura H. et al.
肺線維化への免疫抑制剤の影響
免疫抑制剂对肺纤维化的影响
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[延永瑞希, 小袋加奈絵, 倉内祐樹, 久恒昭哲, 関貴弘, 筒井正人, 香月博志, 山崎璃沙,松澤康雄,川島辰夫,柳原まどか,中村浩之,藤野裕道,村山俊彦]
通讯作者:
山崎璃沙,松澤康雄,川島辰夫,柳原まどか,中村浩之,藤野裕道,村山俊彦
細胞内コレステロール輸送におけるセラミドキナーゼの関与
神经酰胺激酶参与细胞内胆固醇转运
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[江森俊介, 中村浩之, 藤野裕道, 村山俊彦]
通讯作者:
村山俊彦
共 27 条
Epidemiological studies on environmental chemicals as risk factors for chronic sinusitis, including nasal polyps
-
批准号:19K22751
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$3.99万
-
财政年份:2019
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
A Study on Strategic Decision Accounting System for Global Business Investment
-
批准号:16K03981
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.66万
-
财政年份:2016
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Development of new preventive methods for food allergy using of the analysis on epigenetics on lymphocytes and intestinal flora microbiome
-
批准号:15H04783
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.48万
-
财政年份:2015
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Establishment of experimental models for the study of congenital cytomegalovirus infection
-
批准号:24591616
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2012
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Development of Boron Delivery System for Neutron Capture Therapy as a Minimally Invasive Cancer Therapy
-
批准号:23390013
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.9万
-
财政年份:2011
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
A functional MRI study on the regulation of stress mediated brain activity by biting.
-
批准号:22592063
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2010
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Newly development of liposomes vaccines using influenza virus andT cell epitope peptide derived from Japanese cedar pollen
-
批准号:22659121
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.08万
-
财政年份:2010
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
The role of extracellular matrix degradation enzymes, MMP and ADAM in tumor micro environment (stem cell niche)
-
批准号:22592030
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2010
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Electric field induced metallic state in oxide channel field-effect transistors
-
批准号:20840029
-
项目类别:Grant-in-Aid for Young Scientists (Start-up)
-
资助金额:$2.1万
-
财政年份:2008
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Determination and molecular and genetic marker in the allergy produced by RS virus infection and its prevention
-
批准号:20390170
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.65万
-
财政年份:2008
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
DEVELOPING THE MANAGEMENT ACCOUNTING SYSTEM OF JAPANESE SUBSIDIARIES IN CHINA
-
批准号:19530402
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.91万
-
财政年份:2007
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Retinotopy and areal organization of the third tier visual cortex
-
批准号:18591912
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.56万
-
财政年份:2006
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Development of Tyrosine Kinase Inhibitors Based on the Structures of Target Protein
-
批准号:18350090
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.27万
-
财政年份:2006
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Prevention for allergic diseases by clarification of interaction between environmental chemicals and genes of eosinophil-related protein
-
批准号:17390174
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.14万
-
财政年份:2005
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Search of tow-dimensional metallic state in a transition metal sulfide BaVS3 showing a metal-insulator transition
-
批准号:16540326
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.56万
-
财政年份:2004
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Cash Flow Estimation for Environmental Capital Investment
-
批准号:16530290
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.47万
-
财政年份:2004
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Research on the Evaluation of Color Space and Developing Three Dimensional Color Simulator.
-
批准号:16091215
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
-
资助金额:$7.68万
-
财政年份:2004
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Objective evaluation of design for an OS screen using eye movement
-
批准号:13670345
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.26万
-
财政年份:2001
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Study on preventing systems of fetus for uteroplacental circulatory disturbances and uteroplacental dysfunctions produced by microwaves
-
批准号:13470079
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2001
-
负责人:NAKAMURA Hiroyuki
-
依托单位:
Development of monitoring system for effects of ultra low level microwave with changing
-
批准号:12557035
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.13万
-
财政年份:2000
-
负责人:NAKAMURA Hiroyuki
-
依托单位: