The vision/proprioception interaction on brain function during lifting of an object : a PET study

本研究探讨了视觉和本体感受器在皮层和皮层下激活中的相互作用。应用H_2^<15>O正电子发射断层扫描（PET）技术，对22例正常人在有视觉和无视觉（闭眼状态）下抓握和举起小物体时的局部血流量（rCBF）进行了测量。此外，窗帘的效果，抑制了对象的看法和手的动作对rCBF。视觉引导与无视觉静息相比较，皮层结构中的M1/S1/ SMA、PM、CMA、Broadman 's7（BA 7）、11、17和18以及皮层下结构中的小脑被激活。这些区域（BA 7、11、17、18和19除外）在无视觉情况下的移位过程中被激活。视觉和无视觉条件的直接比较也揭示了这些方面的显着差异。在眼前有眼帘时，BA 7、17、18、19（上半部分）和40的活性低于无眼帘时。有幕时BA 45/47、17、19（下部）、21和基底节区的活性高于无幕时。这些结果清楚地表明，视觉和本体感觉的相互作用，在皮层和皮层下的活动，在提升的对象的存在。结果表明，血流分布是根据感觉的需要而制定的

The interaction effect of visual and proprioceptor senses on cortical and subcortical activation was investigated in the present study. Using H_2^<15>O positron emission tomography (PET) with normal human subjects (n = 22), we measured regional blood flow (rCBF) during grasping and lifting of a small object with and without vision (eye-closed condition). In addition, the effect of a curtain that inhibited the view of the object and hand movements on rCBF. With the visual guidance compared with the no-vision rest, the M1/S1/ SMA, PM, CMA, Broadman's 7 (BA7), 11, 17 and 18 in the cortical structures, and cerebellum in the subcortical structure were activated. These areas except for BA7, 11, 17, 18 and 19 were activated during lifting without vision. A direct comparison of the vision and no-vision conditions also revealed a significant difference in these. With the curtain in front of the eyes, less activity were found for BA7, 17, 18, 19 (the upper part) and 40 compared with without the curtain. The activities in BA45/47, 17, 19 (the lower part) and 21, and the basal ganglia were higher with the curtain than without the curtain. These results clearly indicate the presence of vision and proprioception interaction in cortical and subcortical activity during lifting of an object. The results suggest that blood flow distribution is made based on the need of sensory