The vision/proprioception interaction on brain function during lifting of an object : a PET study

本研究探讨了视觉和本体感受器对皮层和皮层下激活的交互作用。采用H_2^<15>正电子发射断层扫描（PET）对22例正常受试者进行了有视力和无视力（闭眼）抓举小物体时的区域血流量（rCBF）测量。此外，窗帘抑制了对物体的观察和手部运动对rCBF的影响。视觉引导与无视觉休息相比，皮质结构M1/S1/ SMA、PM、CMA、Broadman's 7 （BA7）、11、17和18以及皮质下结构小脑被激活。除BA7、11、17、18和19外，其余区域在无视力的情况下被激活。直接比较有视力和无视力的情况也显示出这些方面的显著差异。有帘子遮挡时，BA7、17、18、19（上半部分）和ba40的活动性较无帘子遮挡时减弱。BA45/47、ba17、ba19（下半部分）、ba21和基底神经节的活性在有帷幕的情况下明显高于无帷幕的情况。这些结果清楚地表明，在抬起物体时，皮层和皮层下活动中存在视觉和本体感觉的相互作用。结果表明，血流分布是根据感觉需要而定的

The interaction effect of visual and proprioceptor senses on cortical and subcortical activation was investigated in the present study. Using H_2^<15>O positron emission tomography (PET) with normal human subjects (n = 22), we measured regional blood flow (rCBF) during grasping and lifting of a small object with and without vision (eye-closed condition). In addition, the effect of a curtain that inhibited the view of the object and hand movements on rCBF. With the visual guidance compared with the no-vision rest, the M1/S1/ SMA, PM, CMA, Broadman's 7 (BA7), 11, 17 and 18 in the cortical structures, and cerebellum in the subcortical structure were activated. These areas except for BA7, 11, 17, 18 and 19 were activated during lifting without vision. A direct comparison of the vision and no-vision conditions also revealed a significant difference in these. With the curtain in front of the eyes, less activity were found for BA7, 17, 18, 19 (the upper part) and 40 compared with without the curtain. The activities in BA45/47, 17, 19 (the lower part) and 21, and the basal ganglia were higher with the curtain than without the curtain. These results clearly indicate the presence of vision and proprioception interaction in cortical and subcortical activity during lifting of an object. The results suggest that blood flow distribution is made based on the need of sensory