The vision/proprioception interaction on brain function during lifting of an object : a PET study

本研究探讨了视觉和本体感受器的相互作用对皮层和皮质下激活的影响。应用正电子发射计算机断层扫描(PET)对22例正常人(n=22)在有视力和无视力(闭眼)状态下抓取和抬起小物体的局部血流量(RCBF)进行了测量。此外，遮挡物体视线和手部运动的窗帘对rCBF的影响。视觉引导与非视觉休息相比，皮质结构中的M1/S1/SMA、PM、CMA、Broadman‘s7(Ba7)、11、17、18以及皮质下结构中的小脑均被激活。除Ba7、11、17、18和19外，这些区域在举重过程中被激活，没有视觉。视力和非视力状况的直接比较也显示出这些方面的显著差异。在有窗帘的情况下，Ba7、17、18、19(上半部分)和40的活动量比不戴窗帘的要少。BA45/47、BA17、BA19(下部)、BA45/47、BA45/47、BA17、BA19(下部)、BA21、BA45/47、BA45/47、BA17、BA19、BA21、BA45/47、BA47/47、BA17、BA19、BA21、BA45/47、BA45/47、BA17、BA19、BA45/47、BA45/47、BA17、BA19(下部)、BA21、BA45/47、BA45/这些结果清楚地表明，在举起物体的过程中，皮层和皮质下活动中存在视觉和本体感觉的相互作用。结果表明，血液流量的分配是基于感觉的需要。

The interaction effect of visual and proprioceptor senses on cortical and subcortical activation was investigated in the present study. Using H_2^<15>O positron emission tomography (PET) with normal human subjects (n = 22), we measured regional blood flow (rCBF) during grasping and lifting of a small object with and without vision (eye-closed condition). In addition, the effect of a curtain that inhibited the view of the object and hand movements on rCBF. With the visual guidance compared with the no-vision rest, the M1/S1/ SMA, PM, CMA, Broadman's 7 (BA7), 11, 17 and 18 in the cortical structures, and cerebellum in the subcortical structure were activated. These areas except for BA7, 11, 17, 18 and 19 were activated during lifting without vision. A direct comparison of the vision and no-vision conditions also revealed a significant difference in these. With the curtain in front of the eyes, less activity were found for BA7, 17, 18, 19 (the upper part) and 40 compared with without the curtain. The activities in BA45/47, 17, 19 (the lower part) and 21, and the basal ganglia were higher with the curtain than without the curtain. These results clearly indicate the presence of vision and proprioception interaction in cortical and subcortical activity during lifting of an object. The results suggest that blood flow distribution is made based on the need of sensory