Effects of exercise training on age-related muscle atrophy and bone loss and their countermeasures
运动训练对年龄相关性肌肉萎缩和骨质流失的影响及对策
基本信息
- 批准号:15500478
- 负责人:
- 金额:$ 2.37万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2003
- 资助国家:日本
- 起止时间:2003 至 2004
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Sixty-, 70-, and 80-years old healthy women were subjected to exercise training with their 50, 70, or 100% of maximal voluntary knee extension for 8 weeks. Maximal muscle strength at 60- and 70-years-old women was higher than that at 80-years-old women after exercise training with their 100% of maximal contraction. In contrast, there was no difference in maximal muscle strength among 60-, 70-, and 80-years-old women after their 50 and 70% of maximal contraction. There was no difference in bone density among three groups, irrespective the type of exercise training. An age-related decline in maximal muscle strength was prevented by exercise training with their maximal effort. In contrast, a decrease in bone density was not prevented by exercise training. It is concluded that exercise training at higher strength is effective for muscle strength, but not for bone density. Effects of voluntary running exercise on skeletal muscle and bone in senescence accelerated mouse prone 6 (SAMP6) were investigated. An age-related atrophy in muscle fibers was prevented by exercise training. In addition, an osteopenia was inhibited by exercise training. It is suggested that exercise training is effective for age-related changes in musculoskeletal systems.
60岁、70岁和80岁的健康女性进行了为期8周的50%、70%或100%的最大随意膝关节伸展运动训练。60岁和70岁女性在100%最大收缩运动训练后的最大肌力高于80岁女性。相比之下,60岁、70岁和80岁的女性在最大收缩50%和70%后的最大肌肉力量没有差异。三组之间的骨密度没有差异,无论运动训练的类型如何。最大努力的运动训练可以防止与年龄相关的最大肌肉力量下降。相反,运动训练不能防止骨密度降低。结论:高强度的运动训练对肌肉力量有效,但对骨密度无效。研究了自主跑步运动对加速老化小鼠6(SAMP6)骨骼肌和骨的影响。通过运动训练防止了与年龄相关的肌纤维萎缩。此外,通过运动训练抑制骨质减少。提示运动训练对肌肉骨骼系统的增龄性变化有效。
项目成果
期刊论文数量(16)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Growth-related changes in cell body size and succinate dehydrogenase activity of spinal motoneurons innervating the rat soleus muscle
神经支配大鼠比目鱼肌的脊髓运动神经元的细胞体大小和琥珀酸脱氢酶活性的生长相关变化
- DOI:
- 发表时间:2003
- 期刊:
- 影响因子:0
- 作者:Ishihara A;et al.
- 通讯作者:et al.
Effects of aging and exercise on density and cross-sectional area of femur in senescence-accelerated mouse prone 6
衰老和运动对加速衰老小鼠股骨密度和横截面积的影响 6
- DOI:
- 发表时间:2003
- 期刊:
- 影响因子:0
- 作者:Ishihara;A.;Roy;R.R.;Ohira;Y.;Kawano;F.;Nonaka;K.;Yamamoto;K.;Edgerton;V.R.
- 通讯作者:V.R.
Hyperbaric exposure with high oxygen concentration enhance oxidative capacity of neuromuscular units
高氧浓度的高压暴露增强神经肌肉单位的氧化能力
- DOI:
- 发表时间:2005
- 期刊:
- 影响因子:0
- 作者:Ishihara A;et al.
- 通讯作者:et al.
Effect of running exercise during recovery from hindlimb unloading on soleus muscle fibers and spinal motoneurons in rat
后肢负重恢复期间跑步运动对大鼠比目鱼肌纤维和脊髓运动神经元的影响
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Ishihara A;et al.
- 通讯作者:et al.
Effects of running exercise during recovery from hindlimb unloading on soleus muscle fibers and spinal motoneurons in rats
大鼠后肢减重恢复期间跑步运动对比目鱼肌纤维和脊髓运动神经元的影响
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Ishihara;A.;Kawano;F.;Ishioka;N.;Oishi;H.;Higashibata;A.;Shimazu;T.;Ohira;Y.
- 通讯作者:Y.
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ISHIHARA Akihiko其他文献
低栄養状態にある後期高齢心不全患者に対する理学療法の工夫
改善营养不良老年心力衰竭患者的物理治疗
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
TANAKA Masayuki;KANAZASHI Miho;MATSUMOTO Tomohiro;KONDO Hiroyo;ISHIHARA Akihiko;FUJINO Hidemi;山科吉弘;片野唆敏,矢野俊之,本間 傑,下村佳奈子,渡辺絢子,大堀克彦,橋本暁佳,三浦哲嗣 - 通讯作者:
片野唆敏,矢野俊之,本間 傑,下村佳奈子,渡辺絢子,大堀克彦,橋本暁佳,三浦哲嗣
水中歩行時の運動負荷量の違いが高齢者の呼吸筋疲労に及ぼす影響
水下行走运动负荷差异对老年人呼吸肌疲劳的影响
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
TANAKA Masayuki;KANAZASHI Miho;MATSUMOTO Tomohiro;KONDO Hiroyo;ISHIHARA Akihiko;FUJINO Hidemi;山科吉弘 - 通讯作者:
山科吉弘
ISHIHARA Akihiko的其他文献
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{{ truncateString('ISHIHARA Akihiko', 18)}}的其他基金
Effects of exercise on muscle strength and blood flow in elderly
运动对老年人肌肉力量和血流量的影响
- 批准号:
22500662 - 财政年份:2010
- 资助金额:
$ 2.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Exercise-duration and -intensity and blood volume for maintenance and improvement in health and physical fitness of elderly
维持和改善老年人健康和体质的运动持续时间、强度和血容量
- 批准号:
19500563 - 财政年份:2007
- 资助金额:
$ 2.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Strength and duration for maintenance of muscle volume and bone density during old age
老年时维持肌肉体积和骨密度的强度和持续时间
- 批准号:
13680023 - 财政年份:2001
- 资助金额:
$ 2.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Examination of Exercise Program for Improvement of Age-Related Decreases in Muscle Strength
检查运动计划以改善与年龄相关的肌肉力量下降
- 批准号:
11680025 - 财政年份:1999
- 资助金额:
$ 2.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Reduction of Preserved Capacity for Skeletal Muscle with Aging and Effect of Exercise
骨骼肌保存能力随衰老的减少和运动的影响
- 批准号:
09680101 - 财政年份:1997
- 资助金额:
$ 2.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
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