Development of Optimum Design, Trial Production and Evaluation Systems for Knee Joint Prostheses with High Performace Similar to Natural Synovial Joints

类天然滑膜关节高性能膝关节假体优化设计、试制及评价系统开发

基本信息

  • 批准号:
    04555038
  • 负责人:
  • 金额:
    $ 8.32万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Developmental Scientific Research (B)
  • 财政年份:
    1992
  • 资助国家:
    日本
  • 起止时间:
    1992 至 1994
  • 项目状态:
    已结题

项目摘要

The object of this research is to develop the systems for optimum design, trial production and evaluation of knee prostheses with high performance.The following methods were carried out.[Three-dimensional geometrical analysis of natural knee joints] Geometrical analysis was carried out based on geometrical measurement of natural knee joint model by laser displacement meter. Changes in radius of femoral surfaces between stance and swing phases were shown. Contact analysis indicated the occurrence of rolling motion during severe phase. Surface profiles extracted from the Magnetic Resonance Images were analyzed. Surface remodeling were proposed by minimizing the strain energy.[Trial production and evaluation] Several kinds of geometrical models were proposed on the basis of geometrical analysis of natural knee joint. Cylindrical.duo-cylindrical, spherical and remodeling models were produced from acrylic resin and ultrahigh molecular weight polyethylene by personal computer controlled NC machine. The tibia component of PVA (polyvinylalcohol) hydrogel were prepared by molding-thawing method. New type of knee joint simulator to simulate walking motion was manufactured to evaluate of dynamic characteristics of knee prostheses. Fluid film formation and frictional behavior were observed.[Optimum design with adaptive multimode lubrication] The design concept of adaptive multimode lubrication for knee prostheses was proposed from the summarization of this research project. It was shown that geometrical design with better congruity or with appropriate radius, and the application of compliant materials accompanied with boundary lubricating ability enhance the lubricating performance. The design direction was shown for clinical application.
本研究的目的是开发高性能膝关节假体的优化设计、试制和评估系统。采用了以下方法:【自然膝关节三维几何分析】利用激光位移仪对自然膝关节模型进行几何测量,进行几何分析。在站立和摆动阶段显示股骨表面半径的变化。接触分析表明,在严重阶段发生了滚动运动。分析了从磁共振图像中提取的表面轮廓。采用应变能最小化的方法进行表面重构。在对天然膝关节进行几何分析的基础上,提出了几种不同的几何模型。圆柱形。以丙烯酸树脂和超高分子量聚乙烯为原料,采用微机控制的数控机床制作了双圆柱形、球形和重塑模型。采用成型-解冻法制备PVA(聚乙烯醇)水凝胶胫骨组分。为评估膝关节假体的动态特性,研制了一种模拟行走运动的新型膝关节模拟器。观察了流体膜的形成和摩擦行为。【基于自适应多模态润滑的优化设计】在总结本课题的基础上,提出了膝关节假体自适应多模态润滑的设计理念。结果表明,采用较好的一致性几何设计或适当的半径设计,以及采用具有边界润滑能力的柔顺材料均可提高润滑性能。为临床应用指明了设计方向。

项目成果

期刊论文数量(30)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Teruo Murakami: "Design Concept of Adaptive Multimode Lubrication in Artificial Joints" Design of Amenity. 319-327 (1995)
Teruo Murakami:“人工关节自适应多模式润滑的设计理念”舒适设施设计。
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    0
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S.Hirokawa: "In vitro measurment of pattelar-femoral joint contact pressure during various kinds of walking" 計測自動制御学会論文集. vol.29. 940-948 (1993)
S. Hirokawa:“各种步行过程中髌骨-股骨关节接触压力的体外测量”仪器与控制工程师学会会刊第 29 卷(1993 年)。
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    0
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大月伸男: "人工膝関節における形状と潤滑機能" 日本臨床バイオメカニクス. Vol.14. 229-232 (1993)
大月伸夫:“人工膝关节的形状和润滑功能”日本临床生物力学第 14 卷(1993 年)。
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  • 影响因子:
    0
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  • 通讯作者:
Shunji Hirokawa: "In-vitro Measurement of Patellofemoral Joint Contact Pressure During Various Kinds of Walking" Trans.Soc.Instrument and Control Engrs. Vol.29, No.8. 940-948 (1993)
Shunji Hirokawa:“各种步行过程中髌股关节接触压力的体外测量” Trans.Soc.Instrument and Control Engrs。
  • DOI:
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  • 影响因子:
    0
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T.Murakami: "軟質摩擦面を有する人工膝関節における流体潤滑機能(続報)" 整形外科バイオメカニクス. vol.13. 371-374 (1992)
T. Murakami:“具有软摩擦表面的人工膝关节的流体动力润滑功能(后续)”骨科生物力学第 13 卷(1992 年)。
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MURAKAMI Teruo其他文献

MURAKAMI Teruo的其他文献

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{{ truncateString('MURAKAMI Teruo', 18)}}的其他基金

Elucidation of adaptive lubrication mechanism with low friction and minimum wear in natural synovial joints and development of artificial hydrogel cartilage with super lubricity based on bionic design
阐明自然滑膜关节中低摩擦和最小磨损的自适应润滑机制,并开发基于仿生设计的超润滑人工水凝胶软骨
  • 批准号:
    23000011
  • 财政年份:
    2011
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Specially Promoted Research
Development of reversing agent for multidrug resistance and new chemotherapy by utilizing genistein
利用金雀异黄素开发多药耐药逆转剂及新型化疗药物
  • 批准号:
    18590162
  • 财政年份:
    2006
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Elucidation of Adaptive Multimode Lubrication Mechanism, Self-Organization and Restoration Mechanism in Natural Synovial Joints
阐明自然滑膜关节的自适应多模式润滑机制、自组织和恢复机制
  • 批准号:
    15200037
  • 财政年份:
    2003
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Micro- and Nano-Scopic Biomechanics of Articular Cartilage Focusing Chondrocytes and Surrounding Tissue
关节软骨的微观和纳米生物力学聚焦软骨细胞和周围组织
  • 批准号:
    15086212
  • 财政年份:
    2003
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research on Priority Areas
Elucidation of Adaptive Multimode Lubrication Mechanism and Self-Organization in Natural Synovial Joints
自然滑膜关节自适应多模式润滑机制和自组织的阐明
  • 批准号:
    12480265
  • 财政年份:
    2000
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of Optimum Design, Trial Production and Evaluation Systems for Knee Joint Prostheses with Artificial Cartilage and Meniscus Similar to Natural Synovial Joints
类似天然滑膜关节的人工软骨和半月板膝关节假体优化设计、试制及评价系统开发
  • 批准号:
    11358014
  • 财政年份:
    1999
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Effect of endocrine disrupting chemicals on host defense mechanism (transpoter, enzymes)
内分泌干​​扰化学物质对宿主防御机制(转运蛋白、酶)的影响
  • 批准号:
    11557200
  • 财政年份:
    1999
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Joint Study on the Development of Novel Joint Prostheses
新型关节假体开发联合研究
  • 批准号:
    10044165
  • 财政年份:
    1998
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B).
Elucidation of Adaptive Multimode Lubrication Mechanism in Natural Synovial Joints from Hierarchic and Microscopic Viewpoints
从层次和微观角度阐明自然滑膜关节的自适应多模式润滑机制
  • 批准号:
    09480254
  • 财政年份:
    1997
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Lubrication Mechanism in Natural and Artificial Joints
自然关节和人工关节的润滑机制
  • 批准号:
    07044159
  • 财政年份:
    1995
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for international Scientific Research

相似海外基金

Poroelasticity and lubrication mechanisms of cartilage in natural synovial joints
自然滑膜关节软骨的孔隙弹性和润滑机制
  • 批准号:
    2277372
  • 财政年份:
    2019
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Studentship
Elucidation of adaptive lubrication mechanism with low friction and minimum wear in natural synovial joints and development of artificial hydrogel cartilage with super lubricity based on bionic design
阐明自然滑膜关节中低摩擦和最小磨损的自适应润滑机制,并开发基于仿生设计的超润滑人工水凝胶软骨
  • 批准号:
    23000011
  • 财政年份:
    2011
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Specially Promoted Research
Establishing Links with China in the area of Biotribology of Natural Synovial Joints and Artificial Replacements
在自然滑膜关节和人工关节的生物摩擦学领域与中国建立联系
  • 批准号:
    EP/E041019/1
  • 财政年份:
    2007
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Research Grant
Elucidation of Adaptive Multimode Lubrication Mechanism, Self-Organization and Restoration Mechanism in Natural Synovial Joints
阐明自然滑膜关节的自适应多模式润滑机制、自组织和恢复机制
  • 批准号:
    15200037
  • 财政年份:
    2003
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Elucidation of Adaptive Multimode Lubrication Mechanism and Self-Organization in Natural Synovial Joints
自然滑膜关节自适应多模式润滑机制和自组织的阐明
  • 批准号:
    12480265
  • 财政年份:
    2000
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of Optimum Design, Trial Production and Evaluation Systems for Knee Joint Prostheses with Artificial Cartilage and Meniscus Similar to Natural Synovial Joints
类似天然滑膜关节的人工软骨和半月板膝关节假体优化设计、试制及评价系统开发
  • 批准号:
    11358014
  • 财政年份:
    1999
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Elucidation of Adaptive Multimode Lubrication Mechanism in Natural Synovial Joints from Hierarchic and Microscopic Viewpoints
从层次和微观角度阐明自然滑膜关节的自适应多模式润滑机制
  • 批准号:
    09480254
  • 财政年份:
    1997
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Elucidation of Adaptive Multimode Lubrication, Deterioration and Restoration in Natural Synovial Joints
自然滑膜关节自适应多模式润滑、恶化和恢复的阐明
  • 批准号:
    07458237
  • 财政年份:
    1995
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of Optimun Design, Trial Production and Evaluation Systems for Knee Joint Prostheses with High Performace Similar to Natural Synovial Joints
类天然滑膜关节高性能膝关节假体优化设计、试制及评价系统开发
  • 批准号:
    07558256
  • 财政年份:
    1995
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Adaptive Multimode Lubrication in Natural Synovial Joints and Joint Prostheses
自然滑膜关节和关节假体中的自适应多模式润滑
  • 批准号:
    03452117
  • 财政年份:
    1991
  • 资助金额:
    $ 8.32万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (B)
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