权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Development of Optimun Design, Trial Production and Evaluation Systems for Knee Joint Prostheses with High Performace Similar to Natural Synovial Joints

类天然滑膜关节高性能膝关节假体优化设计、试制及评价系统开发

基本信息

批准号：
07558256
负责人：
MURAKAMI Teruo
金额：
$ 1.41万
依托单位：
KYUSHU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1997
项目状态：
已结题

项目摘要

The object of this research is to develop the systems for optimum design, trial production and evaluation of knee prostheses with high performance.The following method were carried out.[Three-dimensional geometrical analysis of natural knee joints and proposition of geometrical design for knee prostheses] Geometrical analysis was carried out based on geometrical measurement of natural knee joint model by laser displacement meter or Magnetic Resonance Images. On the basis of geometrical analysis, adaptive surface remodeling design was proposed by minimizing the strain energy during walking motion. Duo-cylindrical design was proposed to improve the recovery of fluid film formation during walking motion.[Trial production and evaluation] Cylindrical, duo-cylindrical, spherical and remodeling models were produced from acrylic resin and ultrahigh molecular weight polyethylene by personal computer controlled NC machine. Some components were prepared from stainless steel. The artificial cartil … More age of PVA (polyvinylalcohol) hydrogel, semi-interpenatrating network hydrogel or silicone rubber were applied for knee prostheses. Fluid film formation and frictional behavior for these models were observed. Effectiveness of adaptive surface remodeling and duo-cylindrical design was evaluated in simulatot test. The knee prostheses of elliptical conjunction showed superiority in transverse design for compliant surface. The wear tests of existing knee prostheses of anatomical design exhibited that the tribological severity controls wear modes. Cine-radiography was applied for the motion analysis of knee prostheses in patients.[Optimun design with adaptive multimode lubrication] The design concept of adaptive multimode lubrication for knee prostheses was proposed from the summarization of this research project. It was shown that geometrical design with better congruity or with appropriate radius, and the application of compliant materials accompanied with boundary lubricating ability enhance the lubricating performance. The boundary lubrication by protein molecules was examined by atomic force microscopy (AFM) .The design direction was shown for clinical application. Less

本研究旨在开发高性能膝关节假体的优化设计、试制和评价系统。本研究采用以下方法：[自然膝关节的三维几何分析和假体几何设计的提出]基于激光位移仪或磁共振成像对自然膝关节模型的几何测量进行几何分析。在几何分析的基础上，提出了以行走过程中的应变能最小为目标的自适应曲面重构设计。为了提高行走过程中流体膜的回收率，提出了双圆柱形设计。[试制与评价]以丙烯酸树脂和超高相对分子质量聚乙烯为原料，在个人计算机控制的数控机床上制作了圆柱形、双圆柱形、球形和重塑模型。有些部件是用不锈钢制成的。人造卡蒂尔…膝关节假体多采用PVA水凝胶、半插层网络水凝胶或硅橡胶假体。对这些模型的液膜形成和摩擦行为进行了观察。在模拟试验中评价了自适应表面重塑和双圆柱设计的有效性。椭圆形关节假体在柔顺面的横向设计上显示出优越性。现有解剖设计的膝关节假体的磨损试验表明，摩擦学严重程度控制磨损模式。将电影摄影技术应用于膝关节假体的运动分析。[自适应多模式润滑优化设计]在总结本研究项目的基础上，提出了膝关节假体自适应多模式润滑的设计思想。结果表明，采用重合度较好或半径适中的几何设计，以及采用具有边界润滑能力的柔顺材料，可提高其润滑性能。利用原子力显微镜(AFM)研究了蛋白质分子的边界润滑作用，为临床应用指明了方向。较少