Microevolution and genetic adaptation among Asians
Microevolution and genetic adaptation among Asians
批准号:
10440254
负责人:
ISHIDA Takafumi
金额:
$6.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999
中文摘要
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英文摘要
To reveal relationships between genetic adaptation and human microevolution, we have studied malaria resistant genetic traits.1. Duffy blood group of which antigen is a receptor for vivax malaria was screened serologically and molecularly among these populations. Specimens of weakly reacted type were identified, whereas, Fy allele was not found.2. As for the relationships between SAO (Southeast Asian ovalocytosis) and malaria species, difference in the resistance to malaria by the species was not observed.3. In the Raute of Nepal who are suffering from malaria, their frequency of Fya was rather low among Asian populations.4. The distribution of 27-base pair deletion in the band 3 gene can be super imposed onto the Austronesian speaking populations.5. Screening of G6PD deficiency among untested groups was done.
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Shimizu, Y., Ao, H., Soemantri, Ag., Tiwawech, D., Settheetham-Ishida, W., Kayame, O.W., Nishioka, T. and Ishida, T.: "Sero- and molecular-typing of Duffy blood group in Southeast Asians and Oceaniams : demonstration of cryptic genotypes by the PCR-RFLP s
Shimizu, Y.、Ao, H.、Soemantri, Ag.、Tiwawech, D.、Settheetham-Ishida, W.、Kayame, O.W.、Nishioka, T. 和 Ishida, T.:“Duffy 的血清和分子分型
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作者:
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通讯作者:
Kimura, M. et al.: "Twenty seven base pair deletion in erythrocyte band 3 protein gene responsible for Southeast Asian ovalocytosis is not common among Southeast Asian."Human Biology. 70. 993-1000 (1998)
Kimura, M. 等人:“导致东南亚卵形红细胞增多症的红细胞带 3 蛋白基因中的 27 个碱基对缺失在东南亚人中并不常见。”人类生物学。
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Takao,S.et al.: "Seroprevalence of human T-lymphotropic retrovirus type-1 in Papua New Guinea and Irian Jaya"J.Clin.Virol.. 16. 127-131 (2000)
Takao,S.et al.:“巴布亚新几内亚和伊里安查亚人类 T 淋巴细胞逆转录病毒 1 型血清阳性率”J.Clin.Virol.. 16. 127-131 (2000)
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Kimura et al.: "Twenty seven base a parideletion in erythrocyte band 3 protein gene responsible for Southeast Asian ovalocytasis is not common amous Southeast Asian"Hum. Biol.. 70. 993-1000 (1998)
Kimura 等人:“负责东南亚卵细胞增多症的红细胞带 3 蛋白基因中的 27 个碱基 a 部分缺失在东南亚人中并不常见”哼。
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作者:
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通讯作者:
Kimura et al.: "Twenty seven base pair deletion in erythrocyte band 3 protein gene responsible for Southeast Asian ovalocytosis is not common among Southeast Asians"Hum. Biol.. 70. 993-1000 (1998)
Kimura 等人:“导致东南亚卵形红细胞增多症的红细胞带 3 蛋白基因中的 27 个碱基对缺失在东南亚人中并不常见”Hum。
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