Microevolution and genetic adaptation among Asians

为了揭示遗传适应与人类微进化之间的关系，我们研究了抗疟疾遗传性状。Duffy血型的抗原是间日疟的受体，在这些人群中进行了血清学和分子筛选。鉴定出弱反应型标本，未发现Fy等位基因.至于SAO（东南亚卵细胞增多症）与疟疾种属间的关系，不同种属间对疟疾的抗性差异并不明显.在患有疟疾的尼泊尔Raute人中，他们的Fya频率在亚洲人群中相当低。条带3基因中27个碱基缺失的分布可以叠加到南岛语族人群中.在未检测组中进行G6PD缺乏症筛查。

To reveal relationships between genetic adaptation and human microevolution, we have studied malaria resistant genetic traits.1. Duffy blood group of which antigen is a receptor for vivax malaria was screened serologically and molecularly among these populations. Specimens of weakly reacted type were identified, whereas, Fy allele was not found.2. As for the relationships between SAO (Southeast Asian ovalocytosis) and malaria species, difference in the resistance to malaria by the species was not observed.3. In the Raute of Nepal who are suffering from malaria, their frequency of Fya was rather low among Asian populations.4. The distribution of 27-base pair deletion in the band 3 gene can be super imposed onto the Austronesian speaking populations.5. Screening of G6PD deficiency among untested groups was done.