Development of high accurate monitoring system for human brain by the optical CT method

光学CT法高精度人脑监测系统的研制

• 批准号: 13650809
• 负责人: OKANO Yasunori
• 金额: $ 1.66万
• 依托单位: Shizuoka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13650809/
• 关键词: Optical-CT; Monte Carlo method; Numerical simulation

Since a brain tumor and cerebral infarction are comparatively easy to undergo an operation in the case that the diameter is less than 1cm, findings of them are very important. Then, in order to investigate the detection limited condition of the optical intensity, the size of diameters of a disease part was changed and the influence of the optical intensity detected was investigated by using numerical simulation. An analysis model is a sphere with a diameter of 100mm, and imitated each portion by changing an absorption coefficient supposing the skin, a skull, white matter, and the disease part. Since there is no variation in a solution in the optical intensity detected for the diameter of 6mm or more and the difference fully appeared in the optical intensity at the time of a disease and health as a result of analysis, it is thought that discovery of a disease part is possible. Next, in order to investigate the relation of optical intensity to the position of a disease part, five disease parts have been arranged at equal intervals on the straight line of a light source and a detector using the above-mentioned. At the point near a light source, the detected optical intensity does not have a difference at the time of health and a disease, and has not specified existence of a disease part. However, it is considered by rotating 180 degrees the position of an object or a light source that existence of a disease part can be checked the above result that the existence of the disease within a brain 1cm or less can be detected by Optical-CT by rotating a subject object even if a disease part is in which positions. Since the safe medical checkup that does not use X-rays by using this method was attained, it was shown that sick prevention is possible.

由于脑肿瘤和脑梗塞在直径小于1 cm的情况下相对容易手术，因此它们的发现是非常重要的。然后，为了研究光强的检测极限条件，通过改变病变部位的直径大小，通过数值模拟研究了光强对检测结果的影响。分析模型是直径为100 mm的球体，并且通过改变假设皮肤、头骨、白质和疾病部分的吸收系数来模拟每个部分。由于在直径为6 mm或更大的溶液中检测的光强度没有变化，并且作为分析的结果，在疾病和健康时的光强度中完全出现差异，因此认为发现疾病部分是可能的。接下来，为了研究光强度与疾病部分的位置的关系，使用上述方法在光源和检测器的直线上等间隔地布置了五个疾病部分。在光源附近的点上，检测到的光强度在健康和疾病时没有差别，并且没有指定疾病部分的存在。然而，通过将对象或光源的位置旋转180度，可以认为可以检查疾病部分的存在。上述结果是，即使疾病部分位于哪个位置，也可以通过旋转对象来通过光学-CT来检测大脑1 cm或更小的范围内的疾病的存在。由于使用这种方法获得了不使用X射线的安全体检，因此证明了疾病预防是可能的。

项目成果

H.Kawara, Y.Okano, M.Sudoh: "Development of Numerical code for obtaining accurate brain information by using Optical-Computed Tomography"Proceedings of JICAST. 280-283 (2002)

H.Kawara、Y.Okano、M.Sudoh：“利用光学计算机断层扫描技术获取准确大脑信息的数字代码的开发”JICAST 论文集。

H.Kawara and Y.Okano: "Simulation of optical propagation for development optical-CT"Proceedings of The Yokkaichi Meeting of the Society of Chemical Engineers. Japan. T204 (2002)

H.Kawara 和 Y.Okano：“光学传播模拟以开发光学 CT”化学工程师学会四日市会议记录。

H.Kawara, Y.Okano and M.Sudoh: "Numerical simulation for high accurate brain imaging by using Optical-Computed-Tomography"Proceedings of The 35th Autumn Meeting of the Society of Chemical Engineers. Japan. 83 (2002)

H.Kawara、Y.Okano 和 M.Sudoh：“使用光学计算机断层扫描进行高精度脑成像的数值模拟”化学工程师学会第 35 届秋季会议论文集。

河原一, 岡野泰則: "光CT開発のための光伝播シミュレーション"化学工学会第35回秋季大会研究発表講演要旨集. T204 (2002)

Hajime Kawahara、Yasunori Okano：“光学 CT 开发的光传播模拟”化学工程师学会第 35 届秋季会议 T204（2002 年）研究报告摘要。