Predicting reaction norms of enzyme and metabolite concentrations in Arabidopsis thaliana exposed to different nitrogen availability and temperature regimes (B05)

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B5 (Nikoloski) studies the plasticity of plant metabolism and growth to nitrogen availability and to temperature. Directly measuring the metabolic fluxes that convert carbon and nutrients into the building blocks for plant growth is very challenging. Thus, the project will use advanced metabolic modelling and thermodynamic metabolic flux analysis to study the reaction norms of protein and metabolite concentrations in response to the two environmental cues. The influence of network position of a given metabolite on the shape of its reaction norms and the limits to its plasticity will be analysed, and plasticity genes will be identified.