Development of re-entrant type hyperthermia system for many different kinds of deep tumor

多种深部肿瘤折返式热疗系统的研制

基本信息

  • 批准号:
    16390345
  • 负责人:
  • 金额:
    $ 7.55万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    2004
  • 资助国家:
    日本
  • 起止时间:
    2004 至 2006
  • 项目状态:
    已结题

项目摘要

In this research, a new re-entrant type hyperthermia system was developed to heat many different kinds of deep tumor without contact. Below, the main results of this research are shown.(1) The electromagnetic field and temperature distributions inside the cavity were estimated by 3-D FEM. From these results, it was shown that the proposed heating method was useful for deep tumor hyperthermia.(2) The re-entrant resonant cavity type hyperthermia system for deep tumors was designed and constructed based on the computer simulations.・Developed system consists of a cavity, impedance matching unit, an RF amplifier, an antenna, a computer.・From the results of computer simulations and experimental heating, it was possible to heat the deep tumor of about 2-5cm in diameter by using the different resonance modes (TM010 and TM012-like-modes) without contact.・Moving the position of the object, the position of maximum temperature could be controlled.・Comparing the computer simulation and the experimental results, resonant frequencies agreed with each other with an error of 1% or less, and temperature distributions agreed with each other with an error of 10%.(3) The influence of electromagnetic waves is a social big problem. Leaked electromagnetic field of the developed system hardly has bad influence on the circumferenceIt was found that the proposed heating system could be applicable to heat many different kinds of tumors, noncontact, corresponding to the size and that position where it occurred.
本研究开发了一种新型的再入式热疗系统,可对多种深部肿瘤进行非接触式热疗。下面是这项研究的主要成果。(1)利用三维有限元法计算了腔体内的电磁场和温度分布。从这些结果可以看出,所提出的加热方法对于肿瘤深部热疗是有用的。(2)在计算机模拟的基础上,设计并构建了一种用于深部肿瘤热疗的再入式谐振腔系统。系统由谐振腔、阻抗匹配单元、射频放大器、天线、计算机组成。根据计算机模拟和实验加热的结果,可以通过使用不同的谐振模式(TM 010和TM 012-like模式)无接触地加热直径约2-5cm的深部肿瘤。·移动物体的位置,可以控制最高温度的位置。·将计算机模拟结果与实验结果进行比较,谐振频率与误差在1%以内,温度分布与误差在10%以内。(3)电磁波的影响是一个社会大问题。11所研制的系统的泄漏电磁场几乎不对周围产生不良影响。研究发现,所提出的加热系统可以适用于加热许多不同类型的肿瘤,非接触,对应于大小和发生的位置。

项目成果

期刊论文数量(23)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Development of the re-entrant type resonant cavity applicator for brain tumor hyperthermia -Experimental heating results -
用于脑肿瘤热疗的凹入式谐振腔治疗器的开发-实验加热结果-
脳腫瘍の非接触温熱治療を目的とした空胴共振器アプリケータの設計・試作
用于脑肿瘤非接触式热处理的空腔谐振器涂抹器的设计和原型
Improvement of the resonant cavity applicator for brain tumor Hyperthermia -Computer simulation results-
脑肿瘤热疗谐振腔治疗器的改进-计算机模拟结果-
深部癌の非接触温熱治療を目的とした空胴共振器アプリケータの設計・試作(第3報,試作加温システムによる人体形状寒天ファントムおよび動物の加温実験)
用于深部癌症非接触式热处理的腔体谐振器涂抹器的设计和原型(第三次报告,使用原型加热系统的人形琼脂模型和动物加热实验)
  • DOI:
  • 发表时间:
    2004
  • 期刊:
  • 影响因子:
    0
  • 作者:
    加藤和夫;和田森直;松田甚一;高橋英明;宇塚岳夫;田中隆一
  • 通讯作者:
    田中隆一
Design and Construction of Resonant Cavity Applicater for Brain Tumor Hyperthermia Treatment without Contanct
脑肿瘤非接触热疗共振腔施热器的设计与构建
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KATO Kazuo其他文献

KATO Kazuo的其他文献

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{{ truncateString('KATO Kazuo', 18)}}的其他基金

Post earnings announcement drift after management forecasts
管理层预测后盈利公告后的偏差
  • 批准号:
    21530485
  • 财政年份:
    2009
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The study on the method to estimate the bacterial ecology for oral biofilm, by mapping the quantitative distribution of the biofilm elements.
通过绘制生物膜元素的数量分布来估计口腔生物膜细菌生态的方法研究。
  • 批准号:
    20592477
  • 财政年份:
    2008
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of support system for heating tumors without contact
开发非接触加热肿瘤支持系统
  • 批准号:
    20591485
  • 财政年份:
    2008
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
A study of time-series analysis on Open Source LMS specialized for Practical student experiment
针对学生实践实验的开源LMS的时间序列分析研究
  • 批准号:
    19500815
  • 财政年份:
    2007
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
An empirical study of managerial earnings forecast and it's market reaction
管理层盈余预测及其市场反应的实证研究
  • 批准号:
    19530421
  • 财政年份:
    2007
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
STUDY ON SNP OF GH GENES FAVORING BEEF PRODUCTION
促进牛肉生产的GH基因SNP研究
  • 批准号:
    19380150
  • 财政年份:
    2007
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Study on bacterial ecology and structural permeability within dental plaque using a quantitative method for mapping the distribution pattern of plaque bacteria
使用定量方法研究牙菌斑内的细菌生态和结构渗透性以绘制牙菌斑细菌的分布模式
  • 批准号:
    17592192
  • 财政年份:
    2005
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Empirical examination of disclosure environment in Japan - quarterly earnings announcements and management forecasts -
日本信息披露环境的实证检验——季度收益公告和管理层预测——
  • 批准号:
    16530310
  • 财政年份:
    2004
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
STUDY ON A METHOD FOR MAPPING THE DISTRIBUTION PATTERN OF CARIOGENIC BACTERIA WITHIN DENTAL PLAQUE in vivo USING REAL-TIME PCR
实时荧光定量PCR绘制体内牙菌斑内致龋菌分布模式的方法研究
  • 批准号:
    14571974
  • 财政年份:
    2002
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The interaction between vasopressin and oxytocin neurons after central salt loading
中枢盐负荷后加压素和催产素神经元之间的相互作用
  • 批准号:
    13670068
  • 财政年份:
    2001
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

相似海外基金

Development of polyglycerol-based polymeric nanomotor bearing a stimuli-responsive surface for precise theranostics at deep tumor tissue
开发基于聚甘油的聚合物纳米电机,该电机具有刺激响应表面,可用于深部肿瘤组织的精确治疗诊断
  • 批准号:
    23K17213
  • 财政年份:
    2023
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Evaluation of tumor heterogeneity by deep tumor imaging and control of drug delivery system
深度肿瘤成像评价肿瘤异质性及药物输送系统控制
  • 批准号:
    15K06871
  • 财政年份:
    2015
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
DEVELOPMENT OF RE-ENTRANT TYPE RESONANT CAVITY APPLICATOR FOR DEEP TUMOR HYPERTHERMIA
凹入式谐振腔深部肿瘤热疗治疗仪的研制
  • 批准号:
    08557056
  • 财政年份:
    1996
  • 资助金额:
    $ 7.55万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
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