Molecular epidemiology using new diagnostic methods, therapy and prevention for pediatric viral infection in Asia

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Molecular epidemiological studies of HIV, rubella virus, 11 types of diarrheal viruses and 7 types of respiratory viruses were conducted in children in Asia. Overall, the results of the molecular epidemiological studies in Asia were similar to those in Japan. It was interesting to find that the reassortant strains of viruses among human and animal were observed in Asia. Moreover, we also discovered the new strains of the viruses. Our studies demonstrated that pigs, calves and environmental contaminations were served as the original sources for virus infection to human. This issue rises the important concerning of zoonosis infection. Our epidemic survey study of rubella virus also suggested that the rubella vaccine is necessary in developing countries.