Mechanism of biosynthesis for circular antibacterial peptides produced by lactic acid bacteria from human intestines
Mechanism of biosynthesis for circular antibacterial peptides produced by lactic acid bacteria from human intestines
批准号:
19580076
负责人:
KAWAI Yasushi
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
ヒトの腸管に住んでいる安全性の高い乳酸菌は、抗菌物質を生産し、整腸作用や食品保存に貢献している。本研究では、乳酸菌によって作られるタンパク質性の抗菌物質(バクテリオシン)に着目し、熱や酸に安定性を与えるタンパク質(通常は一本の鎖状で存在している)のリング(環状)構造形成に関わる因子(遺伝子)を特定することに成功した。本成果は、世界で初めての事例であり、現在、論文を作成中である。
英文摘要
ヒトの腸管に住んでいる安全性の高い乳酸菌は、抗菌物質を生産し、整腸作用や食品保存に貢献している。本研究では、乳酸菌によって作られるタンパク質性の抗菌物質(バクテリオシン)に着目し、熱や酸に安定性を与えるタンパク質(通常は一本の鎖状で存在している)のリング(環状)構造形成に関わる因子(遺伝子)を特定することに成功した。本成果は、世界で初めての事例であり、現在、論文を作成中である。
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DOI:
10.3168/jds.2008-1240
发表时间:
2009-06-01
期刊:
JOURNAL OF DAIRY SCIENCE
影响因子:
3.5
作者:
[Arakawa, K., Kawai, Y., Saito, T.]
通讯作者:
Saito, T.
Negative effect of divalent metal cations on production of gassericin T a bacteriocin produced by Lactobacillus gasseri, in milk-based media
二价金属阳离子对奶基培养基中加氏乳杆菌产生的加氏菌素 T 的负面影响
DOI:
--
发表时间:
2009
期刊:
International Dairy Journal(in press)
影响因子:
--
作者:
[Kensuke Arakawa, Yasushi Kawai, Junko Nishimura, Haruki Kitazawa and Tadao Saito]
通讯作者:
Haruki Kitazawa and Tadao Saito
Application of bacteriocin produced by probiotic Lactobacillus gasseri LA39 to biopreservation of custard cream.
益生菌格氏乳杆菌LA39产生的细菌素在蛋奶冻生物保藏中的应用
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[K. Arakawa, Y. Kawai, et. al.]
通讯作者:
et. al.
ガセリシンAの生産方法及び食品保存剤
Gasericin A的生产方法及食品防腐剂
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1128/aem.02485-08
发表时间:
2009-03-01
期刊:
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
影响因子:
4.4
作者:
[Kawai, Yasushi, Kusnadi, Joni, Saito, Tadao]
通讯作者:
Saito, Tadao
共 22 条
Development of antimicrobial agent for antimicrobial peptide "nisin" in ethanol and its action mechanism
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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负责人:KAWAI Yasushi
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A Study of Medieval Local Social History Based on Documents from Kongoji Temple in Kawachi Province
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Study of the Actual Situation on Establishment and Development of the Kyoto Obanyaku
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依托单位:
A food preservation technology and the action mechanism analysis using ethanol with an antibacterial peptide "nisin"
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Biosynthesis mechanism of a cyclic antibacterial peptide linked at N- and C- terminal amino acids and elucidation of the cyclization significance
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A Learning style's effects on and changes in all-English classes.
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A Historical Study of the Compilation Process of Heike monogatari
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The Study of Establishing the System of Special Needs Education Based on the Principle of Partnership
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批准号:21530829
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The way of teacher education how for all teachers to acquire knowledge and skills concerning children with disabilities
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Research on peacekeeping policy of the Kamakura Shogunate
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A Research on the Studies of the Aristocratic System of the Six Dynasties
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依托单位:
Future Directions of Parental Partnership Principles in Special Support Education
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Absolute Configuration Determination of Chiral Compounds Using a Novel Crystalline Agent
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Political and historical study of the Kamakura-kaido
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The principle of the parental partnership in the guidance of the schooling for the handicapped children.
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Studies on the Novel Enzymatie Reaction Mechanisms Taking into Account the Enzyme Fluctuations
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负责人:KAWAI Yasushi
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海外基金