Functional characterization of candidate disease genes identified by the efficient bi-allelic insertional mutagenesis
Functional characterization of candidate disease genes identified by the efficient bi-allelic insertional mutagenesis
批准号:
19590274
负责人:
SUZUKI Takeshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
がんの発症や悪性化の分子メカニズムを解明するためには、原因となる遺伝子の同定とその機能解析が重要となる。我々は、ウイルス感染発がんモデルマウスを用いて、発がんに関係する遺伝子を網羅的に同定し、その機能や相互作用を解析している。同定された標的遺伝子のなかでも、タンパク質のメチル化・脱メチル化に関与する酵素群は、がんの新しい分子標的の候補として、特に注目して解析を進めている。
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Involvement of histone methyltransferases and demethylases in cancer identified by retroviral insertional mutagenesis
通过逆转录病毒插入诱变鉴定组蛋白甲基转移酶和去甲基酶与癌症的关系
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Tong, K.I., Padmanabhan, B., Kobayashi, A., Shang, C., Hirotsu, H., Yokoyama, S. and Yamamoto, M., Suzuki T]
通讯作者:
Suzuki T
新規がん抑制遺伝子候補Jmjd5 の機能解析
新型抑癌基因Jmjd5的功能分析
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Ishimura A, Minehata K, Terashima M, Hara T, Suzuki T]
通讯作者:
Suzuki T
meisl regulates the development of endothelial cells in zebrafish
Meisl 调节斑马鱼内皮细胞的发育
DOI:
--
发表时间:
2008
期刊:
Biochem. Biophys. Res. Commun. 347
影响因子:
--
作者:
[Kenichi Minehata, Atsuo Kawahara, Takeshi Suzuki]
通讯作者:
Takeshi Suzuki
Identification of the genes involved in mouse retrovirus-induced leukemia/ lymphoma by high-throughput retroviral tagging
通过高通量逆转录病毒标签鉴定与小鼠逆转录病毒诱导的白血病/淋巴瘤相关的基因
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Suzuki T, Ishimura A, Terashima M]
通讯作者:
Terashima M
DOI:
10.1016/j.bbrc.2008.07.075
发表时间:
2008-10-03
期刊:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子:
3.1
作者:
[Minehata, Ken-ichi, Kawahara, Atsuo, Suzuki, Takeshi]
通讯作者:
Suzuki, Takeshi
共 13 条
RNAi-based pesticides against the hard-to-control spider mite, Tetranychus urticae
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Study of the neutrino-flux via bound state beta-decay of bare 205Tl ions
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Therapeutic strategy for maintenance of lymphocyte function to improve the prognosis of sepsis
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Study on Micro-Library as Town Resources
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Neutron skin of Ni isotopes
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English Communication Programs for Enhancing Japanese Students' Advocacy Skills
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批准号:23520762
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Study on the glutamate-induced spinal neurodysfunction.
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财政年份:2011
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On representation theory from the view point of integrable systems
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负责人:SUZUKI Takeshi
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依托单位:
Functional characterization of candidate disease genes identified by the efficient insertional mutagenesis
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批准号:21590303
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The effect of nicaraven to organ dysfunctions in sepsis
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Epidemiological study between HPV infection and risk of head and neck cancer
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财政年份:2008
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依托单位:
English Communication Education as Advocacy Training:
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Study of the EC and bound state β decay and its half-life on the highly charged ions.
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Algebras related to integrable systems
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Study of AMPA receptor dysfunctions in CNS diseases
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Nuclear radii measurment of Kr isotopes with the fragment separator
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负责人:SUZUKI Takeshi
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English Debate Program as Cross-Cultural Communication Training
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Neutron Halo Structure in exiotic nuclei (^<17>B,^<22>N,^<23>O etc.)
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Fc receptor signal initiation mechanisms at lipid rafts
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Environmental Design from the View Point of "IKATA"
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