Development of Efficient Molecular Transformation Based on Silicon- Carbon or Borane-Carbon Bond Activation

研究了过渡金属催化的基于硅碳键活化的碳碳键形成反应。将金催化和有机催化相结合应用于烯丙基硅烷分子内烯丙基化合成芳酮的概念，导致了酮-酮交叉羟醛取代反应的发展。另一方面，我们成功地从α-(三甲基硅基)-π-烯丙基钯的中间体中生成了碳化钯物种，反应条件非常温和。

Transition metal catalyzed novel carbon-carbon bond formation reactions based on silicon-carbon bond activation have been studied. The concept of combining gold catalysis and organocatalysis applied for intramolecular allylation of allylsilanes to ynones lead to the development of ketone-ketone cross-aldol surrogate reaction. On the other hand, we were able to get succeed in the generation of palladium carbenoide species from α-(trimethylsilyl)-π-allylpalladium intermediate under very mild reaction condition.