Mechanisms of contraction/relaxation of airway smooth muscle : relationship between β-antagonist and Rho-kinase pathway
Mechanisms of contraction/relaxation of airway smooth muscle : relationship between β-antagonist and Rho-kinase pathway
批准号:
19591804
负责人:
SHIBATA Osamu
金额:
$1.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
The results suggest that high concentrations of landiolol could cause airway smooth muscle contraction through the Rho-kinase pathway, but not through the PI response coupled with muscarinic M3 receptors, 5-HT receptors or the activation of L-type Ca(2+) channels.
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会议论文
High concentrations of landiolol, a β1-adrenoceptor antagonist, stimulates smooth muscle contraction of the rat trachea through the Rho-kinase pathway
高浓度兰地洛尔(一种 β1 肾上腺素受体拮抗剂)通过 Rho 激酶途径刺激大鼠气管平滑肌收缩
DOI:
--
发表时间:
2008
期刊:
J Anesth 22
影响因子:
--
作者:
[Saito M, Shibata O, Tsuda A, Makita T, Sumikawa K, Osamu Shibata]
通讯作者:
Osamu Shibata
Hyperosmolarity attenuates the contraction of rat trachea hrough the inhibition of phosphatidylinositol response
高渗透压通过抑制磷脂酰肌醇反应来减弱大鼠气管的收缩
DOI:
--
发表时间:
2008
期刊:
ActaMedicaNagasakiensia 52
影响因子:
--
作者:
[Saito M, Shibata O, Tsuda A, Makita T, Sumikawa K]
通讯作者:
Sumikawa K
Development of Innovative Targeting Hybrid Artificial Pulmonary Surfactant Preparations by Nanomedicine
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批准号:26350534
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.08万
-
财政年份:2014
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负责人:SHIBATA Osamu
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依托单位:
Development of Innovative Targeting Artificial pulmonary surfactant preparations by Nanomedicine
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批准号:23510134
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.49万
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财政年份:2011
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负责人:SHIBATA Osamu
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依托单位:
Basic research and development of de novo-designed peptide/fluorinated carbon hybrid artificial lung surfactant
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批准号:17310075
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.09万
-
财政年份:2005
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负责人:SHIBATA Osamu
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依托单位:
Mechanisms of airway smooth muscle contraction : physio-pharmacologic factors and intracellular signaling pathway
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批准号:15591638
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.79万
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财政年份:2003
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负责人:SHIBATA Osamu
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依托单位:
Effects of Intravenous anesthetics on Phosphatidylinositol Response of Spinal Descending Inhibitory Pathways of Rat
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批准号:10671421
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:1998
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负责人:SHIBATA Osamu
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依托单位:
ROLES OF PHOSPHATIDYLINOSITOL IN THE MECHANISMS INVOLVED IN THE AIRWAY SMOOTH MUSCLE RELAXATION INDUCED BY ATP-SENSITIVE POTASSIUM CHANNEL OPENERS
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批准号:08671750
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.28万
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财政年份:1996
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负责人:SHIBATA Osamu
-
依托单位:
The Study on Two Dimensional Dynamic Process of Ionic Surfactants Composed of Fluorocarbon and Hydrocarbon Ions
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批准号:07672318
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.28万
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财政年份:1995
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负责人:SHIBATA Osamu
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依托单位:
Estimation of ultraviolet radiation as a limiting factor for vertical distribution of plants by studying their ultraviolet resistance.
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批准号:02804054
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.02万
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财政年份:1990
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负责人:SHIBATA Osamu
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依托单位:
海外基金